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Nucleic Acids Research, 1984, Vol. 12, No. 1Part1 397-407
© 1984

MINICOMPUTERS

A common philosophy and FORTRAN 77 software package for implementing and searching sequence databases

Jean-Michel Claverie

Unite d'informatique Scientifique, Institut Pasteur 25 rue du Docteur Roux, 75724 Paris, Cedex 15, France

Received August 10, 1983. I present a common philosophy for implementing the EMBL and GEN BANK (BBH-Los Alamos) nucleic acid sequence databases, as well as the National Biological Foundation (Dayhoff) protein sequence database. The associated FORTRAN 77 fully transportable software package includes: 1) modules for implementing each of these databases from the initial magnetic tape file, 2) modules performing a fast mnemonic access, 3) modules performing key-string access and allowing the definition of user-specific database subsets, 4) a common probe searching module allowing the stacking of multiple combined search requests over the databases. This software is particularly suitable for 32-bit mini/microcomputers but would eventually run on 16-bit computers.


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