Nucleic Acids Research, 1986, Vol. 14, No. 11 4683-4690
© 1986
Articles |
A new method for predicting signal sequence cleavage sites
Research Group for Theoretical Biophysics, Department of Theoretical Physics, Royal Institute of Technology S-100 44 Stockholm, Sweden
Received March 5, 1986. Revised May 5, 1986. Accepted May 5, 1986.
A new method for identifying secretory signal sequences and for predicting the site of cleavage between a signal sequence and the mature exported protein is described. The predictive accuracy is estimated to be around 75–80% for both prokaryotic and eukaryotic proteins.
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