Abteilung für Innere Medizin m.S. Hämatologie und Onkologie, Virchow-Klinikum, Medizinische Fakultät der Humboldt Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin , Germany , ¹ Abteilung für Innere Medizin/Gastroenterologie, Klinikum Großhadern der Ludwig-Maximillians-Universität, Marchioninistrasse 15, 81377 München , Germany and ² Abteilung Molekularbiologie und Bioinformatik, Institut für Molekularbiologie und Biochemie, Freie Universität Berlin, Arnimallee 22, 14197 Berlin , Germany

Received November 21, 1995; Revised and Accepted January 17, 1996

Point mutations in the ras proto-oncogenes are amongst the most frequent changes found in human malignancies ( 1 ) and may have prognostic importance. A variety of methods have been published for the detection of ras mutations ( 2 - 4 ). However, the most frequently used assays . . . [Full Text of this Article]

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