Nucleic Acids Research, Vol 26, Issue 1 198-199, Copyright © 1998 by Oxford University Press
NF Cariello, GR Douglas, NJ Gorelick, DW Hart, JD Wilson and T Soussi
We have created databases and software applications for the analysis of DNA
mutations at the human p53 gene, the human hprt gene and both the rodent
transgenic lacI and lacZ loci. The databases themselves are stand-alone
dBASE files and the software for analysis of the databases runs on
IBM-compatible computers with Microsoft Windows. Each database has a
separate software analysis program. The software created for these
databases permit the filtering, ordering, report generation and display of
information in the database. In addition, a significant number of routines
have been developed for the analysis of single base substitutions. One
method of obtaining the databases and software is via the World Wide Web.
Open the following home page with a Web Browser:
http://sunsite.unc.edu/dnam/mainpage. html . Alternatively, the databases
and programs are available via public FTP from: anonymous@sunsite.unc.edu.
There is no password required to enter the system. The databases and
software are found beneath the subdirectory:
pub/academic/biology/dna-mutations. Two other programs are available at the
site, a program for comparison of mutational spectra and a program for
entry of mutational data into a relational database.
ARTICLES
Databases and software for the analysis of mutations in the human p53 gene, human hprt gene and both the lacI and lacZ gene in transgenic rodents
Glaxo Wellcome, Inc., Medicines Safety Evaluation, 5 Moore Drive, Research Triangle Park, NC 27709, USA. nfc20355@glaxowellcome.com
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