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Nucleic Acids Research, Vol 26, Issue 1 269-270, Copyright © 1998 by Oxford University Press

ARTICLES

APC gene: database of germline and somatic mutations in human tumors and cell lines

P Laurent-Puig, C Beroud and T Soussi
Hopital Laennec Service de Chirurgie Digestive Generale et Oncologique, 42 Rue de Sevres, 75007 Paris, France. pierre.laurent- puig@biomedicale.univ-paris5.fr

A database (http://perso.curie.fr/tsoussi ) is described, in which over 1000 mutations in the human APC gene of tumors (colon cancer predominantly) are compiled from the literature. It includes both molecular information about the mutations and clinical data about the patients. Software has been designed to analyse all this information in the database.
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