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Nucleic Acids Research, Vol 27, Issue 1 186-187, Copyright © 1999 by Oxford University Press

ARTICLES

The viroid and viroid-like RNA database

DA Lafontaine, P Deschenes, F Bussiere, V Poisson and JP Perreault
Departement de Biochimie, Faculte de Medecine, Universite de Sherbrooke, Sherbrooke, Quebec J1H 5N4, Canada.

This is an online database to facilitate research on viroid, viroid- like RNAs and human hepatitis delta virus (vHDV) by presenting a large number of sequences and related data in a comprehensive and user- friendly format (e.g. position of their self-catalytic domains, open reading frame of the vHDV, prediction of the most stable secondary structures, etc.). Most of these RNA species share a common proposed replication pattern known as a DNA-independent rolling circle mechanism. Together, these species form the 'brotherhood' of the smallest known auto-replicable RNAs. This online database is available on the World Wide Web at http://www.callisto.si.usherb.ca/~jpperra
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