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Nucleic Acids Research, Vol 27, Issue 1 318-322, Copyright © 1999 by Oxford University Press


ARTICLES

Expanding the TRANSFAC database towards an expert system of regulatory molecular mechanisms

T Heinemeyer, X Chen, H Karas, AE Kel, OV Kel, I Liebich, T Meinhardt, I Reuter, F Schacherer and E Wingender
Gesellschaft fur Biotechnologische Forschung mbH, Mascheroder Weg 1, D- 38124 Braunschweig, Germany.

TRANSFAC is a database on transcription factors, their genomic binding sites and DNA-binding profiles. In addition to being updated and extended by new features, it has been complemented now by a series of additional database modules. Among them, modules which provide data about signal transduction pathways (TRANSPATH) or about cell types/organs/developmental stages (CYTOMER) are available as well as an updated version of the previously described COMPEL database. The databases are available on the WWW at http://transfac.gbf.de/
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E. Wingender, X. Chen, R. Hehl, H. Karas, I. Liebich, V. Matys, T. Meinhardt, M. Pru{beta}, I. Reuter, and F. Schacherer
TRANSFAC: an integrated system for gene expression regulation
Nucleic Acids Res., January 1, 2000; 28(1): 316 - 319.
[Abstract] [Full Text] [PDF]


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J. Immunol.Home page
D. Ulgiati, L. S. Subrata, and L. J. Abraham
The Role of Sp Family Members, Basic Krupple-Like Factor, and E Box Factors in the Basal and IFN-{gamma} Regulated Expression of the Human Complement C4 Promoter
J. Immunol., January 1, 2000; 164(1): 300 - 307.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
S. S. Broyles, X. Liu, M. Zhu, and M. Kremer
Transcription Factor YY1 Is a Vaccinia Virus Late Promoter Activator
J. Biol. Chem., December 10, 1999; 274(50): 35662 - 35667.
[Abstract] [Full Text] [PDF]


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J. Virol.Home page
M. Audit, J. Déjardin, B. Hohl, C. Sidobre, T. J. Hope, M. Mougel, and M. Sitbon
Introduction of a cis-Acting Mutation in the Capsid-Coding Gene of Moloney Murine Leukemia Virus Extends Its Leukemogenic Properties
J. Virol., December 1, 1999; 73(12): 10472 - 10479.
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Genome ResHome page
D. L. Burgess, C. F. Davis, L. A. Gefrides, and J. L. Noebels
Identification of Three Novel Ca2+ Channel gamma Subunit Genes Reveals Molecular Diversification by Tandem and Chromosome Duplication
Genome Res., December 1, 1999; 9(12): 1204 - 1213.
[Abstract] [Full Text]


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J. Biol. Chem.Home page
N. Ghosh, J. F. Piskurich, G. Wright, K. Hassani, J. P.-Y. Ting, and K. L. Wright
A Novel Element and a TEF-2-like Element Activate the Major Histocompatibility Complex Class II Transactivator in B-lymphocytes
J. Biol. Chem., November 5, 1999; 274(45): 32342 - 32350.
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Genome ResHome page
T. G. Wolfsberg, A. E. Gabrielian, M. J. Campbell, R. J. Cho, J. L. Spouge, and D. Landsman
Candidate Regulatory Sequence Elements for Cell Cycle-Dependent Transcription in Saccharomyces cerevisiae
Genome Res., August 1, 1999; 9(8): 775 - 792.
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JEMHome page
B. Reizis and P. Leder
Expression of the Mouse Pre-T Cell Receptor {alpha} Gene Is Controlled by an Upstream Region Containing a Transcriptional Enhancer
J. Exp. Med., May 17, 1999; 189(10): 1669 - 1678.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
X.-L. Zheng, S. Matsubara, C. Diao, M. D. Hollenberg, and N. C. W. Wong
Activation of Apolipoprotein AI Gene Expression by Protein Kinase A and Kinase C through Transcription Factor, Sp1
J. Biol. Chem., October 6, 2000; 275(41): 31747 - 31754.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
S.-J. Shih, C. Allan, S. Grehan, E. Tse, C. Moran, and J. M. Taylor
Duplicated Downstream Enhancers Control Expression of the Human Apolipoprotein E Gene in Macrophages and Adipose Tissue
J. Biol. Chem., October 6, 2000; 275(41): 31567 - 31572.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
H. Esterbauer, H. Oberkofler, F. Krempler, A. D. Strosberg, and W. Patsch
The Uncoupling Protein-3 Gene Is Transcribed from Tissue-specific Promoters in Humans but Not in Rodents
J. Biol. Chem., November 10, 2000; 275(46): 36394 - 36399.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
M. R. Dusing, E. A. Florence, and D. A. Wiginton
PDX-1 Is Required for Activation in Vivo from a Duodenum-specific Enhancer
J. Biol. Chem., April 20, 2001; 276(17): 14434 - 14442.
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J. Biol. Chem.Home page
L. B. Cavelier, Y. Qiu, J. K. Bielicki, V. Afzal, J.-F. Cheng, and E. M. Rubin
Regulation and Activity of the Human ABCA1 Gene in Transgenic Mice
J. Biol. Chem., May 18, 2001; 276(21): 18046 - 18051.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
J. F. Kurland, R. Kodym, M. D. Story, K. B. Spurgers, T. J. McDonnell, and R. E. Meyn
NF-kappa B1 (p50) Homodimers Contribute to Transcription of the bcl-2 Oncogene
J. Biol. Chem., November 21, 2001; 276(48): 45380 - 45386.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
Z. Borok, X. Li, V. F. J. Fernandes, B. Zhou, D. K. Ann, and E. D. Crandall
Differential Regulation of Rat Aquaporin-5 Promoter/Enhancer Activities in Lung and Salivary Epithelial Cells
J. Biol. Chem., August 18, 2000; 275(34): 26507 - 26514.
[Abstract] [Full Text] [PDF]


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Proc. Natl. Acad. Sci. USAHome page
A. Bernal and D. A. Kimbrell
Drosophila Thor participates in host immune defense and connects a translational regulator with innate immunity
PNAS, May 23, 2000; 97(11): 6019 - 6024.
[Abstract] [Full Text] [PDF]


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Genome ResHome page
Y. Suzuki, T. Tsunoda, J. Sese, H. Taira, J. Mizushima-Sugano, H. Hata, T. Ota, T. Isogai, T. Tanaka, Y. Nakamura, et al.
Identification and Characterization of the Potential Promoter Regions of 1031 Kinds of Human Genes
Genome Res., May 1, 2001; 11(5): 677 - 684.
[Abstract] [Full Text]



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