Nucleic Acids Research, Vol 27, Issue 1 89-94, Copyright © 1999 by Oxford University Press
C Sanchez, C Lachaize, F Janody, B Bellon, L Roder, J Euzenat, F Rechenmann and B Jacq
FlyNets (http://gifts.univ-mrs.fr/FlyNets/FlyNets_home_page.++ +html) is a
WWW database describing molecular interactions (protein-DNA, protein-RNA
and protein-protein) in the fly Drosophila melanogaster. It is composed of
two parts, as follows. (i) FlyNets-base is a specialized database which
focuses on molecular interactions involved in Drosophila development. The
information content of FlyNets-base is distributed among several specific
lines arranged according to a GenBank-like format and grouped into five
thematic zones to improve human readability. The FlyNets database achieves
a high level of integration with other databases such as FlyBase, EMBL,
GenBank and SWISS-PROT through numerous hyperlinks. (ii) FlyNets-list is a
very simple and more general databank, the long-term goal of which is to
report on any published molecular interaction occuring in the fly, giving
direct web access to corresponding s in Medline and in FlyBase. In the
context of genome projects, databases describing molecular interactions and
genetic networks will provide a link at the functional level between the
genome, the proteome and the transcriptome worlds of different organisms.
Interaction databases therefore aim at describing the contents, structure,
function and behaviour of what we herein define as the interactome world.
ARTICLES
Grasping at molecular interactions and genetic networks in Drosophila melanogaster using FlyNets, an Internet database
Laboratoire de Genetique et Physiologie du Developpement, IBDM, Parc Scientifique de Luminy, CNRS Case 907, 13288 Marseille Cedex 09, France.
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