Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow Print PDF (876K) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (5)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Shomer, B.
Right arrow Articles by Yagil, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shomer, B.
Right arrow Articles by Yagil, G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, Vol 27, Issue 22 4491-4500, Copyright © 1999 by Oxford University Press

ARTICLES

Long W tracts are over-represented in the Escherichia coli and Haemophilus influenzae genomes

B Shomer and G Yagil
The European Bioinformatics Institute, Hinxton, Cambridge, UK.

The occurrence of DNA tracts of the three binary base combinations: R.Y, K.M and W;S has been mapped in the complete genomes of Haemophilus influenzae and Escherichia coli. A highly significant over- representation of W tracts is observed in both bacteria. The excess of W tracts is particularly striking in the 10% intercoding regions. Subdivision of intercoding regions into divergent (promoting), convergent (terminating) and sequential subregions shows that the excess of W tracts is most concentrated in the promoter regions. A particularly high excess of W tracts is observed in the first 200 bases 5' upstream of coding start sites. The data suggest that W tracts have a role in promoter function. A function as unwinding centers, analogous to the role of R.Y tracts in eukaryotes, is proposed. R.Y and K.M tracts are only modestly over-represented in the two bacteria.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Nucleic Acids ResHome page
M. Gal, T. Katz, A. Ovadia, and G. Yagil
TRACTS: a program to map oligopurine.oligopyrimidine and other binary DNA tracts
Nucleic Acids Res., July 1, 2003; 31(13): 3682 - 3685.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
P. Lio
Investigating the Relationship Between Genome Structure, Composition, and Ecology in Prokaryotes
Mol. Biol. Evol., June 1, 2002; 19(6): 789 - 800.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.