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Nucleic Acids Research, 2000, Vol. 28, No. 1 136-138
© 2000 Oxford University Press

BodyMap: a human and mouse gene expression database

Teruyoshi Hishiki1,2, Shoko Kawamoto1, Shinichi Morishita2 and Kousaku Okubo1,*

1Institute for Molecular and Cellular Biology, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan and 2Department of Genome Knowledge Discovery System, Institute of Medical Science, University of Tokyo, 4-6-1 Shiroganedai, Minato, Tokyo 108-8639, Japan

BodyMap is a human and mouse gene expression database that has been maintained since 1993. It is based on site-directed 3'-ESTs collected from non-biased cDNA libraries constructed at Osaka University and contains >270 000 sequences from 60 human and 38 mouse tissues. The site-directed nature of the sequence tags allows unequivocal grouping of tags representing the same transcript and provides abundance information for each transcript in different parts of the body. Our collection of ESTs was compared periodically with other public databases for cross referencing. The histological resolution of source tissues and unique cloning strategy that minimized cloning bias enabled BodyMap to support three unique mRNA based experiments in silico. First, the recurrence information for clones in each library provides a rough estimate of the mRNA composition of each source tissue. Second, a user can search the entire data set with nucleotide sequences or keywords to assess expression patterns of particular genes. Third, and most important, BodyMap allows a user to select genes that have a desired expression pattern in humans and mice. BodyMap is accessible through the WWW at http://bodymap.ims.u-tokyo.ac.jp

* To whom correspondence should be addressed. Tel: +81 6 6879 7992; Fax: +81 6 6877 1922; Email: kousaku@imcb.osaka-u.ac.jp


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