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Nucleic Acids Research, 2000, Vol. 28, No. 1 286-288
© 2000 Oxford University Press

The 1999 SWISS-2DPAGE database update

Christine Hoogland1,*, Jean-Charles Sanchez2, Luisa Tonella2, Pierre-Alain Binz1,2,3, Amos Bairoch3, Denis F. Hochstrasser2 and Ron D. Appel1

1Swiss Institute of Bioinformatics, 1 rue Michel-Servet, CH-1211 Genève 4, Switzerland, 2Central Clinical Chemistry Laboratory, Geneva University Hospital, Geneva, Switzerland and 3Department of Medical Biochemistry, University of Geneva, Geneva, Switzerland

SWISS-2DPAGE (http://www.expasy.ch/ch2d/ ) is an annotated two-dimensional polyacrylamide gel electro­phoresis (2-DE) database established in 1993. The current release contains 24 reference maps from human and mouse biological samples, as well as from Saccharomyces cerevisiae, Escherichia coli and Dictyostelium discoideum origin. These reference maps have now 2824 identified spots, corresponding to 614 separate protein entries in the database, in addition to virtual entries for each SWISS-PROT sequence or any user-entered amino acids sequence. Last year improvements in the SWISS-2DPAGE database are as follows: three new maps have been created and several others have been updated; cross-references to newly built federated 2-DE databases have been added; new functions to access the data have been provided through the ExPASy proteomics server.

* To whom correspondence should be addressed. Tel: +41 22 372 6281; Fax: +41 22 372 6198; Email: christine.hoogland@isb-sib.ch


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