Nucleic Acids Research, 2001, Vol. 29, No. 1 123-125
© 2001 Oxford University Press
The Comprehensive Microbial Resource
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
One challenge presented by large-scale genome sequencing efforts is effective display of uniform information to the scientific community. The Comprehensive Microbial Resource (CMR) contains robust annotation of all complete microbial genomes and allows for a wide variety of data retrievals. The bacterial information has been placed on the Web at http://www.tigr.org/CMR for retrieval using standard web browsing technology. Retrievals can be based on protein properties such as molecular weight or hydrophobicity, GC-content, functional role assignments and taxonomy. The CMR also has special web-based tools to allow data mining using pre-run homology searches, whole genome dot-plots, batch downloading and traversal across genomes using a variety of datatypes.
* To whom correspondence should be addressed. Tel: +1 301 838 0200; Fax: +1 301 838 0209; Email: owhite{at}tigr.org Present address: Erin K. Hickey, Motorola, 4088 Commercial Avenue, Northbrook, IL 60062, USA
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K. J. Cheung, V. Badarinarayana, D. W. Selinger, D. Janse, and G. M. Church A Microarray-Based Antibiotic Screen Identifies a Regulatory Role for Supercoiling in the Osmotic Stress Response of Escherichia coli Genome Res., February 1, 2003; 13(2): 206 - 215. [Abstract] [Full Text] [PDF]
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I. Uchiyama MBGD: microbial genome database for comparative analysis Nucleic Acids Res., January 1, 2003; 31(1): 58 - 62. [Abstract] [Full Text] [PDF]
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A. M. Earl, M. M. Mohundro, I. S. Mian, and J. R. Battista The IrrE Protein of Deinococcus radiodurans R1 Is a Novel Regulator of recA Expression J. Bacteriol., November 15, 2002; 184(22): 6216 - 6224. [Abstract] [Full Text] [PDF]
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E. M. Dullaghan, C. A. Malloff, A. H. Li, W. L. Lam, and R. W. Stokes Two-dimensional bacterial genome display: a method for the genomic analysis of mycobacteria Microbiology, October 1, 2002; 148(10): 3111 - 3117. [Abstract] [Full Text] [PDF]
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M. W. Covert and B. O. Palsson Transcriptional Regulation in Constraints-based Metabolic Models of Escherichia coli J. Biol. Chem., July 26, 2002; 277(31): 28058 - 28064. [Abstract] [Full Text] [PDF]
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J. E. Galagan, C. Nusbaum, A. Roy, M. G. Endrizzi, P. Macdonald, W. FitzHugh, S. Calvo, R. Engels, S. Smirnov, D. Atnoor, et al. The Genome of M. acetivorans Reveals Extensive Metabolic and Physiological Diversity Genome Res., April 1, 2002; 12(4): 532 - 542. [Abstract] [Full Text] [PDF]
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R. Tobes and J. L. Ramos AraC-XylS database: a family of positive transcriptional regulators in bacteria Nucleic Acids Res., January 1, 2002; 30(1): 318 - 321. [Abstract] [Full Text] [PDF]
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D. H. Haft, B. J. Loftus, D. L. Richardson, F. Yang, J. A. Eisen, I. T. Paulsen, and O. White TIGRFAMs: a protein family resource for the functional identification of proteins Nucleic Acids Res., January 1, 2001; 29(1): 41 - 43. [Abstract] [Full Text] [PDF]
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