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Nucleic Acids Research, 2001, Vol. 29, No. 1 185-188
© 2001 Oxford University Press

HUNT: launch of a full-length cDNA database from the Helix Research Institute

Henrik T. Yudate*, Makiko Suwa, Ryotaro Irie, Hiroshi Matsui, Tetsuo Nishikawa, Yoshitaka Nakamura, Daisuke Yamaguchi, Zhang Zhi Peng, Tomoyuki Yamamoto, Keiichi Nagai, Koji Hayashi, Tetsuji Otsuki, Tomoyasu Sugiyama, Toshio Ota, Yutaka Suzuki1, Sumio Sugano1, Takao Isogai and Yasuhiko Masuho

Helix Research Institute, Inc. 1532-3, Yana, Kisarazu, 292-0812 Chiba, Japan and 1Institute of Medical Science, University of Tokyo, 4-6-1 Shirokane-dai Minato-ku Tokyo 108-8639, Japan

The Helix Research Institute (HRI) in Japan is releasing 4356 HUman Novel Transcripts and related information in the newly established HUNT database. The institute is a joint research project principally funded by the Japanese Ministry of International Trade and Industry, and the clones were sequenced in the governmental New Energy and Industrial Technology Development Organization (NEDO) Human cDNA Sequencing Project. The HUNT database contains an extensive amount of annotation from advanced analysis and represents an essential bioinformatics contribution towards understanding of the gene function. The HRI human cDNA clones were obtained from full-length enriched cDNA libraries constructed with the oligo-capping method and have resulted in novel full-length cDNA sequences. A large fraction has little similarity to any proteins of known function and to obtain clues about possible function we have developed original analysis procedures. Any putative function deduced here can be validated or refuted by complementary analysis results. The user can also extract information from specific categories like PROSITE patterns, PFAM domains, PSORT localization, transmembrane helices and clones with GENIUS structure assignments. The HUNT database can be accessed at http://www.hri.co.jp/HUNT.

* To whom correspondence should be addressed. Tel: +81 438 52 3951; Fax: +81 438 52 3952; Email: yudate{at}hri.co.jp


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