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Nucleic Acids Research, 2001, Vol. 29, No. 1 320-322
© 2001 Oxford University Press

STRBase: a short tandem repeat DNA database for the human identity testing community

Christian M. Ruitberg, Dennis J. Reeder and John M. Butler*

Biotechnology Division, National Institute of Standards and Technology, 100 Bureau Drive, Mail Stop 8311, Gaithersburg, MD 20899-8311, USA

The National Institute of Standards and Technology (NIST) has compiled and maintained a Short Tandem Repeat DNA Internet Database (http://www.cstl.nist.gov/biotech/strbase/) since 1997 commonly referred to as STRBase. This database is an information resource for the forensic DNA typing community with details on commonly used short tandem repeat (STR) DNA markers. STRBase consolidates and organizes the abundant literature on this subject to facilitate on-going efforts in DNA typing. Observed alleles and annotated sequence for each STR locus are described along with a review of STR analysis technologies. Additionally, commercially available STR multiplex kits are described, published polymerase chain reaction (PCR) primer sequences are reported, and validation studies conducted by a number of forensic laboratories are listed. To supplement the technical information, addresses for scientists and hyperlinks to organizations working in this area are available, along with the comprehensive reference list of over 1300 publications on STRs used for DNA typing purposes.

* To whom correspondence should be addressed. Tel: +1 301 975 4049; Fax: +1 301 975 8505; Email: john.butler{at}nist.gov Present address: Dennis J. Reeder, Human Identity Group, Applied Biosystems, Inc., 850 Lincoln Center Drive, Foster City, CA 94404, USA.


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