Nucleic Acids Research, 2002, Vol. 30, No. 1 106-108
© 2002 Oxford University Press
The FlyBase database of the Drosophila genome projects and community literature
FlyBase, The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
FlyBase (http://flybase.bio.indiana.edu/) provides an integrated view of the fundamental genomic and genetic data on the major genetic model Drosophila melanogaster and related species. Following on the success of the Drosophila genome project, FlyBase has primary responsibility for the continual reannotation of the D.melanogaster genome. The ultimate goal of the reannotation effort is to decorate the euchromatic sequence of the genome with as much biological information as is available from the community and from the major genome project centers. The current cycle of reannotation focuses on establishing a comprehensive data set of gene models (i.e. transcription units and CDSs). There are many points of entry to the genome within FlyBase, most notably through maps, gene ontologies, structured phenotypic and gene expression data, and anatomy.
* Correspondence should be addressed to: William M. Gelbart, Harvard University, The Biological Laboratories, 16 Divinity Avenue, Cambridge, MA 02138, USA. Tel: +1 617 495 2906; Fax: +1 617 496 1354; Email: gelbart{at}morgan.harvard.edu Current members of the FlyBase Consortium are: W. Gelbart, L. Bayraktaroglu, M. Crosby, D. Emmert, P. Hradecky, Y. Huang, B. Matthews, S. Russo and F. Smutniak (Biological Laboratories, Harvard University, MA); M. Ashburner, A. de Grey, R. Drysdale, R. Foulger, K. Knight, G. Millburn and C. Yamada (Department of Genetics, University of Cambridge, UK); T. Kaufman, K. Matthews, D. Gilbert, G. Grumbling and V. Strelets (Department of Biology, Indiana University, IN); C. Shemen (NCBI, Bethesda, MD); G. Rubin, E. Frise, N. Harris, J. Kaminker, S. Lewis, B. Marshall, S. Misra, C. Mungall, J. Richter, S. Shu and J. Tupy (University of California, CA, and Lawrence Berkeley National Laboratory).
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
K. Ilic, E. A. Kellogg, P. Jaiswal, F. Zapata, P. F. Stevens, L. P. Vincent, S. Avraham, L. Reiser, A. Pujar, M. M. Sachs, et al. The Plant Structure Ontology, a Unified Vocabulary of Anatomy and Morphology of a Flowering Plant Plant Physiology, February 1, 2007; 143(2): 587 - 599. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. D. Thomas, A. Kejariwal, N. Guo, H. Mi, M. J. Campbell, A. Muruganujan, and B. Lazareva-Ulitsky Applications for protein sequence-function evolution data: mRNA/protein expression analysis and coding SNP scoring tools. Nucleic Acids Res., July 1, 2006; 34(Web Server issue): W645 - W650. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. X. Yu, Z. Guan, and H. A. Nash The mushroom body defect Gene Product Is an Essential Component of the Meiosis II Spindle Apparatus in Drosophila Oocytes Genetics, May 1, 2006; 173(1): 243 - 253. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Kawahara, D. Ritsick, G. Cheng, and J. D. Lambeth Point Mutations in the Proline-rich Region of p22phox Are Dominant Inhibitors of Nox1- and Nox2-dependent Reactive Oxygen Generation J. Biol. Chem., September 9, 2005; 280(36): 31859 - 31869. [Abstract] [Full Text] [PDF] |
||||
![]() |
X. Pan, L. Stein, and V. Brendel SynBrowse: a synteny browser for comparative sequence analysis Bioinformatics, September 1, 2005; 21(17): 3461 - 3468. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. B. Coulthard, N. Nolan, J. B. Bell, and A. J. Hilliker Transvection at the vestigial Locus of Drosophila melanogaster Genetics, August 1, 2005; 170(4): 1711 - 1721. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. L. Tupy, A. M. Bailey, G. Dailey, M. Evans-Holm, C. W. Siebel, S. Misra, S. E. Celniker, and G. M. Rubin Identification of putative noncoding polyadenylated transcripts in Drosophila melanogaster PNAS, April 12, 2005; 102(15): 5495 - 5500. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Yandell, A. M. Bailey, S. Misra, S. Shu, C. Wiel, M. Evans-Holm, S. E. Celniker, and G. M. Rubin A computational and experimental approach to validating annotations and gene predictions in the Drosophila melanogaster genome PNAS, February 1, 2005; 102(5): 1566 - 1571. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Mi, B. Lazareva-Ulitsky, R. Loo, A. Kejariwal, J. Vandergriff, S. Rabkin, N. Guo, A. Muruganujan, O. Doremieux, M. J. Campbell, et al. The PANTHER database of protein families, subfamilies, functions and pathways Nucleic Acids Res., January 1, 2005; 33(suppl_1): D284 - D288. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. E. Hill, M. A. Brasch, A. A. del Campo, L. Doucette-Stamm, J. I. Garrels, J. Glaven, J. L. Hartley, J. R. Hudson Jr., T. Moore, and M. Vidal Academia-Industry Collaboration: An Integral Element for Building "Omic" Resources Genome Res., October 1, 2004; 14(10b): 2010 - 2014. [Full Text] [PDF] |
||||
![]() |
L. C. Bartholomay, W.-L. Cho, T. A. Rocheleau, J. P. Boyle, E. T. Beck, J. F. Fuchs, P. Liss, M. Rusch, K. M. Butler, R. C.-C. Wu, et al. Description of the Transcriptomes of Immune Response-Activated Hemocytes from the Mosquito Vectors Aedes aegypti and Armigeres subalbatus Infect. Immun., July 1, 2004; 72(7): 4114 - 4126. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Yu, N. M. Luscombe, H. X. Lu, X. Zhu, Y. Xia, J.-D. J. Han, N. Bertin, S. Chung, M. Vidal, and M. Gerstein Annotation Transfer Between Genomes: Protein-Protein Interologs and Protein-DNA Regulogs Genome Res., June 1, 2004; 14(6): 1107 - 1118. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Rajaram and H. A. Nash A Specific Alteration in the Electroretinogram of Drosophila melanogaster Is Induced by Halothane and Other Volatile General Anesthetics Anesth. Analg., June 1, 2004; 98(6): 1705 - 1711. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Wilson, A. Battersby, A. Csiszar, E. Vogelsang, and M. Leptin A Functional Domain of Dof That Is Required for Fibroblast Growth Factor Signaling Mol. Cell. Biol., March 15, 2004; 24(6): 2263 - 2276. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Mitri, M.-L. Parmentier, J.-P. Pin, J. Bockaert, and Y. Grau Divergent Evolution in Metabotropic Glutamate Receptors: A NEW RECEPTOR ACTIVATED BY AN ENDOGENOUS LIGAND DIFFERENT FROM GLUTAMATE IN INSECTS J. Biol. Chem., March 5, 2004; 279(10): 9313 - 9320. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. K. Inlow and L. L. Restifo Molecular and Comparative Genetics of Mental Retardation Genetics, February 1, 2004; 166(2): 835 - 881. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. Negre, J. M. Ranz, F. Casals, M. Caceres, and A. Ruiz A New Split of the Hox Gene Complex in Drosophila: Relocation and Evolution of the Gene labial Mol. Biol. Evol., December 1, 2003; 20(12): 2042 - 2054. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. G. Tilney, P. S. Connelly, L. Ruggiero, K. A. Vranich, and G. M. Guild Actin Filament Turnover Regulated by Cross-linking Accounts for the Size, Shape, Location, and Number of Actin Bundles in Drosophila Bristles Mol. Biol. Cell, October 1, 2003; 14(10): 3953 - 3966. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. C. Conant and A. Wagner Asymmetric Sequence Divergence of Duplicate Genes Genome Res., September 1, 2003; 13(9): 2052 - 2058. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Mi, J. Vandergriff, M. Campbell, A. Narechania, W. Majoros, S. Lewis, P. D. Thomas, and M. Ashburner Assessment of Genome-Wide Protein Function Classification for Drosophila melanogaster Genome Res., September 1, 2003; 13(9): 2118 - 2128. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Laurencon, A. Purdy, J. Sekelsky, R. S. Hawley, and T. T. Su Phenotypic Analysis of Separation-of-Function Alleles of MEI-41, Drosophila ATM/ATR Genetics, June 1, 2003; 164(2): 589 - 601. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. D. Pleasance, M. A. Marra, and S. J.M. Jones Assessment of SAGE in Transcript Identification Genome Res., June 1, 2003; 13(6): 1203 - 1215. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. D. King, R. E. Foulger, S. S. Dwight, J. V. White, and F. P. Roth Predicting Gene Function From Patterns of Annotation Genome Res., May 1, 2003; 13(5): 896 - 904. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. Camon, M. Magrane, D. Barrell, D. Binns, W. Fleischmann, P. Kersey, N. Mulder, T. Oinn, J. Maslen, A. Cox, et al. The Gene Ontology Annotation (GOA) Project: Implementation of GO in SWISS-PROT, TrEMBL, and InterPro Genome Res., April 1, 2003; 13(4): 662 - 672. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. M. Overton, L. A. Meadows, J. Urban, and S. Russell Evidence for differential and redundant function of the Sox genes Dichaete and SoxN during CNS development in Drosophila Development, March 11, 2003; 129(18): 4219 - 4228. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. I. Tazuke, C. Schulz, L. Gilboa, M. Fogarty, A. P. Mahowald, A. Guichet, A. Ephrussi, C. G. Wood, R. Lehmann, and M. T. Fuller A germline-specific gap junction protein required for survival of differentiating early germ cells Development, March 7, 2003; 129(10): 2529 - 2539. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Roberg-Perez, C. M. Carlson, and D. A. Largaespada MTID: a database of Sleeping Beauty transposon insertions in mice Nucleic Acids Res., January 1, 2003; 31(1): 78 - 81. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Pattyn, F. Speleman, A. De Paepe, and J. Vandesompele RTPrimerDB: the Real-Time PCR primer and probe database Nucleic Acids Res., January 1, 2003; 31(1): 122 - 123. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Sardiello, F. Licciulli, D. Catalano, M. Attimonelli, and C. Caggese MitoDrome: a database of Drosophila melanogaster nuclear genes encoding proteins targeted to the mitochondrion Nucleic Acids Res., January 1, 2003; 31(1): 322 - 324. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Carter, J. Liu, and B. Rost PEP: Predictions for Entire Proteomes Nucleic Acids Res., January 1, 2003; 31(1): 410 - 413. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. Y. M. Rayburn, H. C. Gooding, S. P. Choksi, D. Maloney, A. R. Kidd III, D. E. Siekhaus, and M. Bender amontillado, the Drosophila Homolog of the Prohormone Processing Protease PC2, Is Required During Embryogenesis and Early Larval Development Genetics, January 1, 2003; 163(1): 227 - 237. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. D. Stein, C. Mungall, S. Shu, M. Caudy, M. Mangone, A. Day, E. Nickerson, J. E. Stajich, T. W. Harris, A. Arva, et al. The Generic Genome Browser: A Building Block for a Model Organism System Database Genome Res., October 1, 2002; 12(10): 1599 - 1610. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Xie, A. Wasserman, Z. Levine, A. Novik, V. Grebinskiy, A. Shoshan, and L. Mintz Large-Scale Protein Annotation through Gene Ontology Genome Res., May 1, 2002; 12(5): 785 - 794. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. E. Smith III, C. A. Cummings, and C. Cronmiller daughterless coordinates somatic cell proliferation, differentiation and germline cyst survival during follicle formation in Drosophila Development, January 7, 2002; 129(13): 3255 - 3267. [Abstract] [Full Text] [PDF] |
||||












