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Nucleic Acids Research, 2002, Vol. 30, No. 1 129-136
© 2002 Oxford University Press

The Celera Discovery SystemTM

Anthony Kerlavage*, Vivien Bonazzi, Matteo di Tommaso, Charles Lawrence, Peter Li, Frank Mayberry, Richard Mural, Marc Nodell, Mark Yandell, Jinghui Zhang and Paul Thomas1

Celera Genomics, 45 W. Gudd Drive, Rockville, MD 20850, USA and 1850 Lincoln Centre Drive, Foster City, CA 94044, USA

The Celera Discovery SystemTM (CDS) is a web-accessible research workbench for mining genomic and related biological information. Users have access to the human and mouse genome sequences with annotation presented in summary form in BioMolecule Reports for genes, transcripts and proteins. Over 40 additional databases are available, including sequence, mapping, mutation, genetic variation, mRNA expression, protein structure, motif and classification data. Data are accessible by browsing reports, through a variety of interactive graphical viewers, and by advanced query capability provided by the LION SRSTM search engine. A growing number of sequence analysis tools are available, including sequence similarity, pattern searching, multiple sequence alignment and Hidden Markov Model search. A user workspace keeps track of queries and analyses. CDS is widely used by the academic research community and requires a subscription for access. The system and academic pricing information are available at http://cds.celera.com.

* To whom correspondence should be addressed. Tel: +1 240 453 3730; Fax: +1 240 453 3885; Email: anthony.kerlavage{at}celera.com


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