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Nucleic Acids Research, 2002, Vol. 30, No. 1 174-175
© 2002 Oxford University Press

Update of AMmtDB: a database of multi-aligned Metazoa mitochondrial DNA sequences

Cecilia Lanave*, Flavio Licciulli1, Mariateresa De Robertis2, Alessandra Marolla1 and Marcella Attimonelli1

Centro di Studio sui Mitocondri e Metabolismo Energetico CNR, Via Amendola 165/A, 70126 Bari, Italy, 1Dipartimento di Biochimica e Biologia Molecolare, Università di Bari, Via E. Orabona 4, 70126 Bari, Italy and 2Dipartimento di Genetica e Anatomia Patologica, Università di Bari, Via E. Orabona 4, 70126 Bari, Italy

The AMmtDB database (http://bighost.area.ba.cnr.it/mitochondriome) has been updated by collecting the multi-aligned sequences of Chordata and Invertebrata mitochondrial genes coding for proteins and tRNAs. Links to the multi-aligned mtDNA intraspecies variants, collected in VarMmtDB at the Mitochondriome web site, have been introduced. The genes coding for proteins are multi-aligned based on the translated sequences and both the nucleotide and amino acid multi-alignments are provided. AMmtDB data selected through SRS can be viewed and managed using GeneDoc or other programs for the management of multi-aligned data depending on the user’s operative system. The multiple alignments have been produced with CLUSTALW and PILEUP programs and then carefully optimized manually.

* To whom correspondence should be addressed. Tel: +39 80 548 2180; Fax: +39 80 548 4467; Email: cecilia{at}area.ba.cnr.it


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