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Nucleic Acids Research, 2002, Vol. 30, No. 1 80-83
© 2002 Oxford University Press

YPL.db: the Yeast Protein Localization database

Georg Habeler, Klaus Natter1, Gerhard G. Thallinger, Matthew E. Crawford1, Sepp D. Kohlwein1 and Zlatko Trajanoski*

Institute of Biomedical Engineering, Graz University of Technology, Krenngasse 37, 8010 Graz, Austria and 1SFB Biomembrane Research Center, Institute of Molecular Biology, Biochemistry and Microbiology, University Graz, Austria

The Yeast Protein Localization database (YPL.db) contains information about the localization patterns of yeast proteins resulting from microscopic analyses. The data and parameters of the experiments to obtain the localization information, together with images from confocal or video microscopy, are stored in a relational database, building an archive of, and the documentation for, all experiments. The database can be queried based on gene name, protein localization, growth conditions and a number of additional parameters. All experiment parameters are selectable from predefined lists to ensure database integrity and conformity across different investigators. The database provides a structure reference resource to allow for better characterization of unknown or ambiguous localization patterns. Links to MIPS, YPD and SGD databases are provided to allow fast access to further information not contained in the localization database itself. YPL.db is available at http://ypl.tugraz.at.

* To whom correspondence should be addressed. Tel: +43 316 873 5332; Fax: +43 316 873 5340; Email: zlatko.trajanoski{at}tugraz.at Present address: Matthew E. Crawford, Proteome Inc., Cummings Center, Suite 435M, Beverly, MA 01915, USA


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