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Nucleic Acids Research, 2003, Vol. 31, No. 1 172-175
© 2003 Oxford University Press

The FlyBase database of the Drosophila genome projects and community literature

The FlyBase Consortium*

FlyBase, The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA

*Correspondence should be addressed to William M. Gelbart, FlyBase, The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA. Tel: +1 6174952906; Fax: +1 6174961354; Email: gelbart{at}morgan.harvard.edu
Current members of the FlyBase Consortium are W. Gelbart, L. Bayraktaroglu, B. Bettencourt, K. Campbell, M. Crosby, D. Emmert, P. Hradecky, Y. Huang, S. Letovsky, B. Matthews, S. Russo, A. Schroeder, F. Smutniak, P. Zhou, and M. Zytkovicz (Biological Laboratories, Harvard University, Cambridge, MA); M. Ashburner, R. Drysdale, A. de Grey, R. Foulger, G. Millburn and C. Yamada (Department of Genetics, University of Cambridge, Cambridge, UK); T. Kaufman, K. Matthews, D. Gilbert, G. Grumbling and V. Strelets (Department of Biology, Indiana University, Bloomington, IN); C. Shemen (NCBI, Bethesda); G. Rubin, B. Berman, E. Frise, M. Gibson, N. Harris, J. Kaminker, S. Lewis, B. Marshall, S. Misra, C. Mungall, S. Prochnik, J. Richter, C. Smith, S. Shu, J. Tupy and C. Wiel (University of California, Berkeley, CA, and Lawrence Berkeley National Laboratories)

ABSTRACT

FlyBase (http://flybase.bio.indiana.edu/) provides an integrated view of the fundamental genomic and genetic data on the major genetic model Drosophila melanogaster and related species. FlyBase has primary responsibility for the continual reannotation of the D. melanogaster genome. The ultimate goal of the reannotation effort is to decorate the euchromatic sequence of the genome with as much biological information as is available from the community and from the major genome project centers. A complete revision of the annotations of the now-finished euchromatic genomic sequence has been completed. There are many points of entry to the genome within FlyBase, most notably through maps, gene products and ontologies, structured phenotypic and gene expression data, and anatomy.


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Two Interdependent TRPV Channel Subunits, Inactive and Nanchung, Mediate Hearing in Drosophila
J. Neurosci., October 13, 2004; 24(41): 9059 - 9066.
[Abstract] [Full Text] [PDF]


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Genome ResHome page
D. E. Hill, M. A. Brasch, A. A. del Campo, L. Doucette-Stamm, J. I. Garrels, J. Glaven, J. L. Hartley, J. R. Hudson Jr., T. Moore, and M. Vidal
Academia-Industry Collaboration: An Integral Element for Building "Omic" Resources
Genome Res., October 1, 2004; 14(10b): 2010 - 2014.
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Mol. Cell. Biol.Home page
F.-L. Sun, K. Haynes, C. L. Simpson, S. D. Lee, L. Collins, J. Wuller, J. C. Eissenberg, and S. C. R. Elgin
cis-Acting Determinants of Heterochromatin Formation on Drosophila melanogaster Chromosome Four
Mol. Cell. Biol., September 15, 2004; 24(18): 8210 - 8220.
[Abstract] [Full Text] [PDF]


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J. Neurosci.Home page
J. Rohrbough, E. Rushton, L. Palanker, E. Woodruff, H. J. G. Matthies, U. Acharya, J. K. Acharya, and K. Broadie
Ceramidase Regulates Synaptic Vesicle Exocytosis and Trafficking
J. Neurosci., September 8, 2004; 24(36): 7789 - 7803.
[Abstract] [Full Text] [PDF]


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GeneticsHome page
D. D. Pollock and J. C. Larkin
Estimating the Degree of Saturation in Mutant Screens
Genetics, September 1, 2004; 168(1): 489 - 502.
[Abstract] [Full Text] [PDF]


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Mol Biol EvolHome page
A. K. Holloway and D. J. Begun
Molecular Evolution and Population Genetics of Duplicated Accessory Gland Protein Genes in Drosophila
Mol. Biol. Evol., September 1, 2004; 21(9): 1625 - 1628.
[Abstract] [Full Text] [PDF]


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Integr. Comp. Biol.Home page
J. D. Fry, C. M. Bahnck, M. Mikucki, N. Phadnis, and W. C. Slattery
Dietary Ethanol Mediates Selection on Aldehyde Dehydrogenase Activity in Drosophila melanogaster
Integr. Comp. Biol., August 1, 2004; 44(4): 275 - 283.
[Abstract] [Full Text] [PDF]


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J. Cell Sci.Home page
L. G. Tilney, P. S. Connelly, and G. M. Guild
Microvilli appear to represent the first step in actin bundle formation in Drosophila bristles
J. Cell Sci., July 15, 2004; 117(16): 3531 - 3538.
[Abstract] [Full Text] [PDF]


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J. Am. Med. Inform. Assoc.Home page
M. A. Shifman, R. Srivastava, C. A. Brandt, T.-R. Li, K. White, and P. L. Miller
Exploring the Portability of Informatics Capabilities from a Clinical Application to a Bioscience Application
J. Am. Med. Inform. Assoc., July 1, 2004; 11(4): 294 - 299.
[Abstract] [Full Text] [PDF]


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GeneticsHome page
A. J. Moehring and T. F. C. Mackay
The Quantitative Genetic Basis of Male Mating Behavior in Drosophila melanogaster
Genetics, July 1, 2004; 167(3): 1249 - 1263.
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GeneticsHome page
A. J. Moehring, J. Li, M. D. Schug, S. G. Smith, M. deAngelis, T. F. C. Mackay, and J. A. Coyne
Quantitative Trait Loci for Sexual Isolation Between Drosophila simulans and D. mauritiana
Genetics, July 1, 2004; 167(3): 1265 - 1274.
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Nucleic Acids ResHome page
M. Stanke, R. Steinkamp, S. Waack, and B. Morgenstern
AUGUSTUS: a web server for gene finding in eukaryotes
Nucleic Acids Res., July 1, 2004; 32(suppl_2): W309 - W312.
[Abstract] [Full Text] [PDF]


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GeneticsHome page
C. Schulz, A. A. Kiger, S. I. Tazuke, Y. M. Yamashita, L. C. Pantalena-Filho, D. L. Jones, C. G. Wood, and M. T. Fuller
A Misexpression Screen Reveals Effects of bag-of-marbles and TGF{beta} Class Signaling on the Drosophila Male Germ-Line Stem Cell Lineage
Genetics, June 1, 2004; 167(2): 707 - 723.
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GeneticsHome page
E. Ryder, F. Blows, M. Ashburner, R. Bautista-Llacer, D. Coulson, J. Drummond, J. Webster, D. Gubb, N. Gunton, G. Johnson, et al.
The DrosDel Collection: A Set of P-Element Insertions for Generating Custom Chromosomal Aberrations in Drosophila melanogaster
Genetics, June 1, 2004; 167(2): 797 - 813.
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Genome ResHome page
J. Stalker, B. Gibbins, P. Meidl, J. Smith, W. Spooner, H.-R. Hotz, and A. V. Cox
The Ensembl Web Site: Mechanics of a Genome Browser
Genome Res., May 1, 2004; 14(5): 951 - 955.
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GeneticsHome page
A. Laurencon, C. M. Orme, H. K. Peters, C. L. Boulton, E. K. Vladar, S. A. Langley, E. P. Bakis, D. T. Harris, N. J. Harris, S. M. Wayson, et al.
A Large-Scale Screen for Mutagen-Sensitive Loci in Drosophila
Genetics, May 1, 2004; 167(1): 217 - 231.
[Abstract] [Full Text] [PDF]


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DevelopmentHome page
M. N. Arbeitman, A. A. Fleming, M. L. Siegal, B. H. Null, and B. S. Baker
A genomic analysis of Drosophila somatic sexual differentiation and its regulation
Development, May 1, 2004; 131(9): 2007 - 2021.
[Abstract] [Full Text] [PDF]


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GeneticsHome page
K. Hirai, S. Toyohira, T. Ohsako, and M.-T. Yamamoto
Isolation and Cytogenetic Characterization of Male Meiotic Mutants of Drosophila melanogaster
Genetics, April 1, 2004; 166(4): 1795 - 1806.
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Nucleic Acids ResHome page
F. A. Kondrashov, A. Y. Ogurtsov, and A. S. Kondrashov
Bioinformatical assay of human gene morbidity
Nucleic Acids Res., March 12, 2004; 32(5): 1731 - 1737.
[Abstract] [Full Text] [PDF]


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DevelopmentHome page
J. H. Thomas and E. Wieschaus
src64 and tec29 are required for microfilament contraction during Drosophila cellularization
Development, February 15, 2004; 131(4): 863 - 871.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
K. Koles, K. D. Irvine, and V. M. Panin
Functional Characterization of Drosophila Sialyltransferase
J. Biol. Chem., February 6, 2004; 279(6): 4346 - 4357.
[Abstract] [Full Text] [PDF]


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GeneticsHome page
K. Sawamura, J. Roote, C.-I Wu, and M.-T. Yamamoto
Genetic Complexity Underlying Hybrid Male Sterility in Drosophila
Genetics, February 1, 2004; 166(2): 789 - 796.
[Abstract] [Full Text] [PDF]


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Mol. Biol. CellHome page
K. Patterson, A. B. Molofsky, C. Robinson, S. Acosta, C. Cater, and J. A. Fischer
The Functions of Klarsicht and Nuclear Lamin in Developmentally Regulated Nuclear Migrations of Photoreceptor Cells in the Drosophila Eye
Mol. Biol. Cell, February 1, 2004; 15(2): 600 - 610.
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Cold Spring Harb Symp Quant BiolHome page
K.A. HAYNES, B.A. LEIBOVITCH, S.H. RANGWALA, C. CRAIG, and S.C.R. ELGIN
Analyzing Heterochromatin Formation Using Chromosome 4 of Drosophila melanogaster
Cold Spring Harb Symp Quant Biol, January 1, 2004; 69(0): 267 - 272.
[Abstract] [PDF]


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J HeredHome page
D. J. Orengo, M. Papaceit, and E. Juan
A Minisatellite with Fold-Back Structure is Included in the 5'-Flanking Region of the Adh Gene of Scaptodrosophila lebanonensis
J. Hered., January 1, 2004; 95(1): 62 - 69.
[Abstract] [Full Text] [PDF]


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Nucleic Acids ResHome page
R. Apweiler, A. Bairoch, C. H. Wu, W. C. Barker, B. Boeckmann, S. Ferro, E. Gasteiger, H. Huang, R. Lopez, M. Magrane, et al.
UniProt: the Universal Protein knowledgebase
Nucleic Acids Res., January 1, 2004; 32(90001): D115 - 119.
[Abstract] [Full Text] [PDF]



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