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Nucleic Acids Research, 2003, Vol. 31, No. 1 400-402
© 2003 Oxford University Press

PRINTS and its automatic supplement, prePRINTS

T. K. Attwood*,1,2, P. Bradley1,2, D. R. Flower3, A. Gaulton1, N. Maudling1, A. L. Mitchell1,2, G. Moulton1, A. Nordle1, K. Paine3, P. Taylor3, A. Uddin1 and C. Zygouri3

1 School of Biological Sciences and Department of Computer Science, The University of Manchester, Manchester M13 9PT, UK 2 EMBL Outstation—European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK 3 Edward Jenner Institute for Vaccine Research, Compton, Newbury, Berkshire RG20 7NN, UK

*To whom correspondence should be addressed. Tel: +44 1612755766; Fax: +44 1612755082; Email: attwood{at}bioinf.man.ac.uk

ABSTRACT

The PRINTS database houses a collection of protein fingerprints. These may be used to assign uncharacterised sequences to known families and hence to infer tentative functions. The September 2002 release (version 36.0) includes 1800 fingerprints, encoding ~11 000 motifs, covering a range of globular and membrane proteins, modular polypeptides and so on. In addition to its continued steady growth, we report here the development of an automatic supplement, prePRINTS, designed to increase the coverage of the resource and reduce some of the manual burdens inherent in its maintenance. The databases are accessible for interrogation and searching at http://www.bioinf.man.ac.uk/dbbrowser/PRINTS/.


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