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Nucleic Acids Research, 2003, Vol. 31, No. 1 424-426
© 2003 Oxford University Press

Database for mobile group II introns

Lixin Dai, Navtej Toor, Robert Olson, Andrew Keeping and Steven Zimmerly*

Department of Biological Sciences, University of Calgary, Calgary, Alberta T2N 1N4, Canada

*To whom correspondence should be addressed: Tel: +403 2207933; Fax: +403 2899311; Email: zimmerly{at}ucalgary.ca

ABSTRACT

Group II introns are self-splicing RNAs and retroelements found in bacteria and lower eukaryotic organelles. During the past several years, they have been uncovered in surprising numbers in bacteria due to the genome sequencing projects; however, most of the newly sequenced introns are not correctly identified. We have initiated an ongoing web site database for mobile group II introns in order to provide correct information on the introns, particularly in bacteria. Information in the web site includes: (1) introductory information on group II introns; (2) detailed information on subfamilies of intron RNA structures and intron-encoded proteins; (3) a listing of identified introns with correct boundaries, RNA secondary structures and other detailed information; and (4) phylogenetic and evolutionary information. The comparative data should facilitate study of the function, spread and evolution of group II introns. The database can be accessed at http://www.fp.ucalgary.ca/group2introns/.


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