Nucleic Acids Research, 2003, Vol. 31, No. 13 3406-3415
© 2003 Oxford University Press
Mfold web server for nucleic acid folding and hybridization prediction
Department of Mathematical Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
*Tel: +1 5182766902; Fax: +1 5182764824; Email: zukerm{at}rpi.edu
The abbreviated name, ‘mfold web server’, describes a number of closely related software applications available on the World Wide Web (WWW) for the prediction of the secondary structure of single stranded nucleic acids. The objective of this web server is to provide easy access to RNA and DNA folding and hybridization software to the scientific community at large. By making use of universally available web GUIs (Graphical User Interfaces), the server circumvents the problem of portability of this software. Detailed output, in the form of structure plots with or without reliability information, single strand frequency plots and ‘energy dot plots’, are available for the folding of single sequences. A variety of ‘bulk’ servers give less information, but in a shorter time and for up to hundreds of sequences at once. The portal for the mfold web server is http://www.bioinfo.rpi.edu/applications/mfold. This URL will be referred to as ‘MFOLDROOT’.
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 A. Cimerman, D. Pacifico, P. Salar, C. Marzachi, and X. Foissac Striking Diversity of vmp1, a Variable Gene Encoding a Putative Membrane Protein of the Stolbur Phytoplasma Appl. Envir. Microbiol., May 1, 2009; 75(9): 2951 - 2957. [Abstract] [Full Text] [PDF]
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 A. San Millan, F. Depardieu, S. Godreuil, and P. Courvalin VanB-Type Enterococcus faecium Clinical Isolate Successively Inducibly Resistant to, Dependent on, and Constitutively Resistant to Vancomycin Antimicrob. Agents Chemother., May 1, 2009; 53(5): 1974 - 1982. [Abstract] [Full Text] [PDF]
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K. T. Gagnon, S.-Y. Ju, M. B. Goshe, E. S. Maxwell, and S. Franzen A role for hydrophobicity in a Diels-Alder reaction catalyzed by pyridyl-modified RNA Nucleic Acids Res., May 1, 2009; 37(9): 3074 - 3082. [Abstract] [Full Text] [PDF]
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B. Szarzynska, L. Sobkowiak, B. D. Pant, S. Balazadeh, W.-R. Scheible, B. Mueller-Roeber, A. Jarmolowski, and Z. Szweykowska-Kulinska Gene structures and processing of Arabidopsis thaliana HYL1-dependent pri-miRNAs Nucleic Acids Res., May 1, 2009; 37(9): 3083 - 3093. [Abstract] [Full Text] [PDF]
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 S. L. Fishman, S. H. Factor, C. Balestrieri, X. Fan, A. M. DiBisceglie, S. M. Desai, G. Benson, and A. D. Branch Mutations in the Hepatitis C Virus core Gene Are Associated with Advanced Liver Disease and Hepatocellular Carcinoma Clin. Cancer Res., May 1, 2009; 15(9): 3205 - 3213. [Abstract] [Full Text] [PDF]
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G. Blakqori, I. van Knippenberg, and R. M. Elliott Bunyamwera Orthobunyavirus S-Segment Untranslated Regions Mediate Poly(A) Tail-Independent Translation J. Virol., April 15, 2009; 83(8): 3637 - 3646. [Abstract] [Full Text] [PDF]
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 R. Batuwita and V. Palade microPred: effective classification of pre-miRNAs for human miRNA gene prediction Bioinformatics, April 15, 2009; 25(8): 989 - 995. [Abstract] [Full Text] [PDF]
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