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Nucleic Acids Research, 2003, Vol. 31, No. 13 3742-3745
© 2003 Oxford University Press

EUGÈNE'HOM: a generic similarity-based gene finder using multiple homologous sequences

Sylvain Foissac*, Philippe Bardou, Annick Moisan, Marie-Josée Cros and Thomas Schiex

Laboratoire de Biométrie et Intelligence Artificielle, INRA, 31326, Castanet Tolosan Cedex, France

*To whom correspondence should be addressed. Tel: +33 5 61 28 53 33; Fax: +33 5 61 28 53 35; Email : foissac{at}toulouse.inra.fr

EUGÈNE'HOM is a gene prediction software for eukaryotic organisms based on comparative analysis. EUGÈNE'HOM is able to take into account multiple homologous sequences from more or less closely related organisms. It integrates the results of TBLASTX analysis, splice site and start codon prediction and a robust coding/non-coding probabilistic model which allows EUGÈNE'HOM to handle sequences from a variety of organisms. The current target of EUGÈNE'HOM is plant sequences. The EUGÈNE'HOM web site is available at http://genopole.toulouse.inra.fr/bioinfo/eugene/EuGeneHom/cgi-bin/EuGeneHom.pl.


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