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Nucleic Acids Research, 2004, Vol. 32, Database issue D101-D103
© 2004 Oxford University Press

The European ribosomal RNA database

Jan Wuyts, Guy Perrière1 and Yves Van de Peer*

Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology (VIB), Ghent University, Technologiepark 927, B-9052 Ghent, Belgium and 1 Laboratoire de Biométrie et Biologie Évolutive—UMR CNRS no. 5558, Université Claude Bernard, Lyon 1, France

*To whom correspondence should be addressed. Tel: +32 9 264 8756; Fax: +32 9 264 5349; Email: yves.vandepeer{at}psb.ugent.be

The European ribosomal RNA database aims to compile all complete or nearly complete ribosomal RNA sequences from both the small (SSU) and large (LSU) ribosomal subunits. All sequences are available in aligned format. Sequence alignment is based on the secondary structure of the molecules, as determined by comparative sequence analysis. Additional information about the sequences, such as taxonomic classification of the organism from which they have been obtained, and literature references are also provided. In order to identify the closest relatives to newly determined sequences, BLAST searches can be performed, after which the best matching sequences are aligned and a phylogenetic tree is inferred. As of 2003, the European ribosomal RNA database is maintained at Ghent University (Belgium). The database can be consulted at http://www.psb.ugent.be/rRNA/.


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