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Nucleic Acids Research, 2004, Vol. 32, Database issue D142-D144
© 2004 Oxford University Press

SMART 4.0: towards genomic data integration

Ivica Letunic, Richard R. Copley1, Steffen Schmidt, Francesca D. Ciccarelli, Tobias Doerks, Jörg Schultz2, Chris P. Ponting3 and Peer Bork*

EMBL, Meyerhofstrasse 1, 69012 Heidelberg, Germany, 1 Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK, 2 Bioinformatik, Biozentrum, Am Hubland, University of Wuerzburg, 97074 Wuerzburg, Germany and 3 MRC Functional Genetics Unit, Department of Human Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK

*To whom correspondence should be addressed. Tel: +49 6221 387 526; Fax: +49 6221 387 517; Email: bork{at}embl-heidelberg.de

SMART (Simple Modular Architecture Research Tool) is a web tool (http://smart.embl.de/) for the identification and annotation of protein domains, and provides a platform for the comparative study of complex domain architectures in genes and proteins. The January 2004 release of SMART contains 685 protein domains. New developments in SMART are centred on the integration of data from completed metazoan genomes. SMART now uses predicted proteins from complete genomes in its source sequence databases, and integrates these with predictions of orthology. New visualization tools have been developed to allow analysis of gene intron–exon structure within the context of protein domain structure, and to align these displays to provide schematic comparisons of orthologous genes, or multiple transcripts from the same gene. Other improvements include the ability to query SMART by Gene Ontology terms, improved structure database searching and batch retrieval of multiple entries.


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Home page
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[Abstract] [Full Text] [PDF]


Home page
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Home page
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Home page
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[Abstract] [Full Text] [PDF]


Home page
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[Abstract] [Full Text] [PDF]


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Home page
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Home page
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Home page
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Home page
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Home page
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Home page
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A "Holistic" Kinesin Phylogeny Reveals New Kinesin Families and Predicts Protein Functions
Mol. Biol. Cell, April 1, 2006; 17(4): 1734 - 1743.
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J. Biol. Chem.Home page
K. M. Short and T. C. Cox
Subclassification of the RBCC/TRIM Superfamily Reveals a Novel Motif Necessary for Microtubule Binding
J. Biol. Chem., March 31, 2006; 281(13): 8970 - 8980.
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Nucleic Acids ResHome page
F. Turlure, G. Maertens, S. Rahman, P. Cherepanov, and A. Engelman
A tripartite DNA-binding element, comprised of the nuclear localization signal and two AT-hook motifs, mediates the association of LEDGF/p75 with chromatin in vivo
Nucleic Acids Res., March 20, 2006; 34(5): 1653 - 1665.
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Proc. Natl. Acad. Sci. USAHome page
S. D. Fugmann, C. Messier, L. A. Novack, R. A. Cameron, and J. P. Rast
An ancient evolutionary origin of the Rag1/2 gene locus
PNAS, March 7, 2006; 103(10): 3728 - 3733.
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Plant CellHome page
M. Kieffer, Y. Stern, H. Cook, E. Clerici, C. Maulbetsch, T. Laux, and B. Davies
Analysis of the Transcription Factor WUSCHEL and Its Functional Homologue in Antirrhinum Reveals a Potential Mechanism for Their Roles in Meristem Maintenance
PLANT CELL, March 1, 2006; 18(3): 560 - 573.
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Mol. Biol. CellHome page
H. Friesen, C. Humphries, Y. Ho, O. Schub, K. Colwill, and B. Andrews
Characterization of the Yeast Amphiphysins Rvs161p and Rvs167p Reveals Roles for the Rvs Heterodimer In Vivo
Mol. Biol. Cell, March 1, 2006; 17(3): 1306 - 1321.
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Mol. Biol. CellHome page
A. J. Wijeratne, C. Chen, W. Zhang, L. Timofejeva, and H. Ma
The Arabidopsis thaliana PARTING DANCERS Gene Encoding a Novel Protein Is Required for Normal Meiotic Homologous Recombination
Mol. Biol. Cell, March 1, 2006; 17(3): 1331 - 1343.
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J. Biol. Chem.Home page
R. N. de Jong, E. AB, T. Diercks, V. Truffault, M. Daniels, R. Kaptein, and G. E. Folkers
Solution Structure of the Human Ubiquitin-specific Protease 15 DUSP Domain
J. Biol. Chem., February 24, 2006; 281(8): 5026 - 5031.
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J. Biol. Chem.Home page
W. Hao, T. Takano, J. Guillemette, J. Papillon, G. Ren, and A. V. Cybulsky
Induction of Apoptosis by the Ste20-like Kinase SLK, a Germinal Center Kinase That Activates Apoptosis Signal-regulating Kinase and p38
J. Biol. Chem., February 10, 2006; 281(6): 3075 - 3084.
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Nucleic Acids ResHome page
B. Titz, S. Thomas, S. V. Rajagopala, T. Chiba, T. Ito, and P. Uetz
Transcriptional activators in yeast
Nucleic Acids Res., February 7, 2006; 34(3): 955 - 967.
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J Exp BotHome page
F. Vinagre, C. Vargas, K. Schwarcz, J. Cavalcante, E. M. Nogueira, J. I. Baldani, P. C. G. Ferreira, and A. S. Hemerly
SHR5: a novel plant receptor kinase involved in plant-N2-fixing endophytic bacteria association
J. Exp. Bot., February 1, 2006; 57(3): 559 - 569.
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J. Bacteriol.Home page
K. Mazouni, G. Pehau-Arnaudet, P. England, P. Bourhy, I. Saint Girons, and M. Picardeau
The Scc Spirochetal Coiled-Coil Protein Forms Helix-Like Filaments and Binds to Nucleic Acids Generating Nucleoprotein Structures
J. Bacteriol., January 15, 2006; 188(2): 469 - 476.
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MicrobiologyHome page
J. Boekhorst, Q. Helmer, M. Kleerebezem, and R. J. Siezen
Comparative analysis of proteins with a mucus-binding domain found exclusively in lactic acid bacteria
Microbiology, January 1, 2006; 152(1): 273 - 280.
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Nucleic Acids ResHome page
M. Y. Galperin
The Molecular Biology Database Collection: 2006 update.
Nucleic Acids Res., January 1, 2006; 34(Database issue): D3 - D5.
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Genome ResHome page
N. L. Barbosa-Morais, M. Carmo-Fonseca, and S. Aparicio
Systematic genome-wide annotation of spliceosomal proteins reveals differential gene family expansion
Genome Res., January 1, 2006; 16(1): 66 - 77.
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Nucleic Acids ResHome page
V. Matys, O. V. Kel-Margoulis, E. Fricke, I. Liebich, S. Land, A. Barre-Dirrie, I. Reuter, D. Chekmenev, M. Krull, K. Hornischer, et al.
TRANSFAC(R) and its module TRANSCompel(R): transcriptional gene regulation in eukaryotes
Nucleic Acids Res., January 1, 2006; 34(suppl_1): D108 - D110.
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Nucleic Acids ResHome page
D. L. Wheeler, T. Barrett, D. A. Benson, S. H. Bryant, K. Canese, V. Chetvernin, D. M. Church, M. DiCuccio, R. Edgar, S. Federhen, et al.
Database resources of the National Center for Biotechnology Information
Nucleic Acids Res., January 1, 2006; 34(suppl_1): D173 - D180.
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Nucleic Acids ResHome page
A. K. L. Leung, L. Trinkle-Mulcahy, Y. W. Lam, J. S. Andersen, M. Mann, and A. I. Lamond
NOPdb: Nucleolar Proteome Database
Nucleic Acids Res., January 1, 2006; 34(suppl_1): D218 - D220.
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Nucleic Acids ResHome page
R. D. Finn, J. Mistry, B. Schuster-Bockler, S. Griffiths-Jones, V. Hollich, T. Lassmann, S. Moxon, M. Marshall, A. Khanna, R. Durbin, et al.
Pfam: clans, web tools and services
Nucleic Acids Res., January 1, 2006; 34(suppl_1): D247 - D251.
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Nucleic Acids ResHome page
I. Letunic, R. R. Copley, B. Pils, S. Pinkert, J. Schultz, and P. Bork
SMART 5: domains in the context of genomes and networks
Nucleic Acids Res., January 1, 2006; 34(suppl_1): D257 - D260.
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Nucleic Acids ResHome page
C. Yeats, M. Maibaum, R. Marsden, M. Dibley, D. Lee, S. Addou, and C. A. Orengo
Gene3D: modelling protein structure, function and evolution
Nucleic Acids Res., January 1, 2006; 34(suppl_1): D281 - D284.
[Abstract] [Full Text] [PDF]



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