Nucleic Acids Research, 2005, Vol. 33, Database issue D34-D38
© 2005, the authors
Nucleic Acids Research, Vol. 33, Database issue © Oxford University Press 2005; all rights reserved
GenBank
Department of Health and Human Services, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
* To whom correspondence should be addressed. Tel: +1 301 435 5950; Fax: +1 301 480 9241; Email: wheeler{at}ncbi.nlm.nih.gov
Received September 15, 2004; Revised and Accepted October 5, 2004
GenBank® is a comprehensive database that contains publicly available DNA sequences for more than 165 000 named organisms, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects. Most submissions are made using the web-based BankIt or standalone Sequin programs and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the EMBL Data Library in the UK and the DNA Data Bank of Japan helps to ensure worldwide coverage. GenBank is accessible through NCBI's retrieval system, Entrez, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, go to the NCBI Homepage at http://www.ncbi.nlm.nih.gov.
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A. S. Hinrichs, D. Karolchik, R. Baertsch, G. P. Barber, G. Bejerano, H. Clawson, M. Diekhans, T. S. Furey, R. A. Harte, F. Hsu, et al. The UCSC Genome Browser Database: update 2006 Nucleic Acids Res., January 1, 2006; 34(suppl_1): D590 - D598. [Abstract] [Full Text] [PDF]
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P. Sangwan, S. Kovac, K. E. R. Davis, M. Sait, and P. H. Janssen Detection and Cultivation of Soil Verrucomicrobia Appl. Envir. Microbiol., December 1, 2005; 71(12): 8402 - 8410. [Abstract] [Full Text] [PDF]
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P. D. Karp, C. A. Ouzounis, C. Moore-Kochlacs, L. Goldovsky, P. Kaipa, D. Ahren, S. Tsoka, N. Darzentas, V. Kunin, and N. Lopez-Bigas Expansion of the BioCyc collection of pathway/genome databases to 160 genomes Nucleic Acids Res., October 24, 2005; 33(19): 6083 - 6089. [Abstract] [Full Text] [PDF]
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G. Cheng, B. Qian, R. Samudrala, and D. Baker Improvement in protein functional site prediction by distinguishing structural and functional constraints on protein family evolution using computational design Nucleic Acids Res., October 13, 2005; 33(18): 5861 - 5867. [Abstract] [Full Text] [PDF]
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L. Goldovsky, P. Janssen, D. Ahren, B. Audit, I. Cases, N. Darzentas, A. J. Enright, N. Lopez-Bigas, J. M. Peregrin-Alvarez, M. Smith, et al. CoGenT++: an extensive and extensible data environment for computational genomics Bioinformatics, October 1, 2005; 21(19): 3806 - 3810. [Abstract] [Full Text] [PDF]
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D. E. Kunzler, S. Sasso, M. Gamper, D. Hilvert, and P. Kast Mechanistic Insights into the Isochorismate Pyruvate Lyase Activity of the Catalytically Promiscuous PchB from Combinatorial Mutagenesis and Selection J. Biol. Chem., September 23, 2005; 280(38): 32827 - 32834. [Abstract] [Full Text] [PDF]
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R. A. George, R. V. Spriggs, G. J. Bartlett, A. Gutteridge, M. W. MacArthur, C. T. Porter, B. Al-Lazikani, J. M. Thornton, and M. B. Swindells Inaugural Article: Effective function annotation through catalytic residue conservation PNAS, August 30, 2005; 102(35): 12299 - 12304. [Abstract] [Full Text] [PDF]
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J. D. Thompson, S. R. Holbrook, K. Katoh, P. Koehl, D. Moras, E. Westhof, and O. Poch MAO: a Multiple Alignment Ontology for nucleic acid and protein sequences Nucleic Acids Res., July 25, 2005; 33(13): 4164 - 4171. [Abstract] [Full Text] [PDF]
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J. H. Havgaard, R. B. Lyngso, and J. Gorodkin The FOLDALIGN web server for pairwise structural RNA alignment and mutual motif search Nucleic Acids Res., July 1, 2005; 33(suppl_2): W650 - W653. [Abstract] [Full Text] [PDF]
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P. Khatri, S. Sellamuthu, P. Malhotra, K. Amin, A. Done, and S. Draghici Recent additions and improvements to the Onto-Tools Nucleic Acids Res., July 1, 2005; 33(suppl_2): W762 - W765. [Abstract] [Full Text] [PDF]
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D. L. Wheeler, B. Smith-White, V. Chetvernin, S. Resenchuk, S. M. Dombrowski, S. W. Pechous, T. Tatusova, and J. Ostell Plant Genome Resources at the National Center for Biotechnology Information Plant Physiology, July 1, 2005; 138(3): 1280 - 1288. [Abstract] [Full Text] [PDF]
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W.J. Kent, F. Hsu, D. Karolchik, R. M. Kuhn, H. Clawson, H. Trumbower, and D. Haussler Exploring relationships and mining data with the UCSC Gene Sorter Genome Res., May 1, 2005; 15(5): 737 - 741. [Abstract] [Full Text] [PDF]
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D. L. Wheeler, T. Barrett, D. A. Benson, S. H. Bryant, K. Canese, D. M. Church, M. DiCuccio, R. Edgar, S. Federhen, W. Helmberg, et al. Database resources of the National Center for Biotechnology Information Nucleic Acids Res., January 1, 2005; 33(suppl_1): D39 - D45. [Abstract] [Full Text] [PDF]
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