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Nucleic Acids Research 2005 33(Database Issue):D374-D377; doi:10.1093/nar/gki023
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Nucleic Acids Research, 2005, Vol. 33, Database issue D374-D377
© 2005, the authors
Nucleic Acids Research, Vol. 33, Database issue © Oxford University Press 2005; all rights reserved

Fungal BLAST and Model Organism BLASTP Best Hits: new comparison resources at the Saccharomyces Genome Database (SGD)

Rama Balakrishnan, Karen R. Christie, Maria C. Costanzo, Kara Dolinski1, Selina S. Dwight, Stacia R. Engel, Dianna G. Fisk, Jodi E. Hirschman, Eurie L. Hong, Robert Nash, Rose Oughtred1, Marek Skrzypek, Chandra L. Theesfeld, Gail Binkley, Qing Dong, Christopher Lane, Anand Sethuraman, Shuai Weng, David Botstein1 and J. Michael Cherry*

Department of Genetics, School of Medicine, Stanford University, Stanford, CA 94305-5120, USA and 1 Lewis-Sigler Institute for Integrative Genomics, Carl Icahn Laboratory, Princeton University, Washington Road, Princeton, NJ 08544, USA

* To whom correspondence should be addressed. Tel: +1 650 723 7541; Fax: +1 650 725 1534; Email: cherry{at}genome.stanford.edu

Received September 15, 2004; Revised and Accepted September 21, 2004

The Saccharomyces Genome Database (SGD; http://www.yeastgenome.org/) is a scientific database of gene, protein and genomic information for the yeast Saccharomyces cerevisiae. SGD has recently developed two new resources that facilitate nucleotide and protein sequence comparisons between S.cerevisiae and other organisms. The Fungal BLAST tool provides directed searches against all fungal nucleotide and protein sequences available from GenBank, divided into categories according to organism, status of completeness and annotation, and source. The Model Organism BLASTP Best Hits resource displays, for each S.cerevisiae protein, the single most similar protein from several model organisms and presents links to the database pages of those proteins, facilitating access to curated information about potential orthologs of yeast proteins.

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