Nucleic Acids Research, 2005, Vol. 33, Database issue D390-D395
© 2005, the authors
Nucleic Acids Research, Vol. 33, Database issue © Oxford University Press 2005; all rights reserved
FlyBase: genes and gene models
Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK and 1 The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
* To whom correspondence should be addressed. Tel: +44 1223 333963; Fax: +44 1223 333992; Email: rd120{at}gen.cam.ac.uk
The FlyBase Consortium: W. Gelbart, K. Campbell, M. Crosby, D. Emmert, B. Matthews, S. Russo, A. Schroeder, F. Smutniak, P. Zhang, P. Zhou and M. Zytkovicz (Biological Laboratories, Harvard University, Cambridge, MA, USA); M. Ashburner, R. Drysdale, A. de Grey, R. Foulger, G. Millburn, D. Sutherland and C. Yamada (Department of Genetics, University of Cambridge, Cambridge, UK); T. Kaufman, K. Matthews, A. DeAngelo, R. K. Cook, D. Gilbert, J. Goodman, G. Grumbling, H. Sheth and V. Strelets (Department of Biology, Indiana University, Bloomington, IN, USA); G. Rubin, M. Gibson, N. Harris, S. Lewis, S. Misra and S. Q. Shu (University of California, Berkeley, CA, USA and Lawrence Berkeley National Laboratories, CA, USA)
Received September 15, 2004; Revised and Accepted September 28, 2004
FlyBase (http://flybase.org) is the primary repository of genetic and molecular data of the insect family Drosophilidae. For the most extensively studied species, Drosophila melanogaster, a wide range of data are presented in integrated formats. Data types include mutant phenotypes, molecular characterization of mutant alleles and aberrations, cytological maps, wild-type expression patterns, anatomical images, transgenic constructs and insertions, sequence-level gene models and molecular classification of gene product functions. There is a growing body of data for other Drosophila species; this is expected to increase dramatically over the next year, with the completion of draft-quality genomic sequences of an additional 11 Drosphila species.
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use permissions, please contact journals.permissions{at}oupjournals.org.
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A. S. Hinrichs, D. Karolchik, R. Baertsch, G. P. Barber, G. Bejerano, H. Clawson, M. Diekhans, T. S. Furey, R. A. Harte, F. Hsu, et al. The UCSC Genome Browser Database: update 2006 Nucleic Acids Res., January 1, 2006; 34(suppl_1): D590 - D598. [Abstract] [Full Text] [PDF]
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H. Liu, Z.-Z. Hu, J. Zhang, and C. Wu BioThesaurus: a web-based thesaurus of protein and gene names Bioinformatics, January 1, 2006; 22(1): 103 - 105. [Abstract] [Full Text] [PDF]
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D. Lyalin, K. Koles, S. D. Roosendaal, E. Repnikova, L. Van Wechel, and V. M. Panin The twisted Gene Encodes Drosophila Protein O-Mannosyltransferase 2 and Genetically Interacts With the rotated abdomen Gene Encoding Drosophila Protein O-Mannosyltransferase 1 Genetics, January 1, 2006; 172(1): 343 - 353. [Abstract] [Full Text] [PDF]
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M. Ashburner and C. M. Bergman Drosophila melanogaster: A case study of a model genomic sequence and its consequences Genome Res., December 1, 2005; 15(12): 1661 - 1667. [Abstract] [Full Text] [PDF]
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M. R. Brent Genome annotation past, present, and future: How to define an ORF at each locus Genome Res., December 1, 2005; 15(12): 1777 - 1786. [Abstract] [Full Text] [PDF]
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E. N. Andreyeva, E. S. Belyaeva, V. F. Semeshin, G. V. Pokholkova, and I. F. Zhimulev Three distinct chromatin domains in telomere ends of polytene chromosomes in Drosophila melanogaster Tel mutants J. Cell Sci., December 1, 2005; 118(23): 5465 - 5477. [Abstract] [Full Text] [PDF]
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A. N. Krasnov, M. M. Kurshakova, V. E. Ramensky, P. V. Mardanov, E. N. Nabirochkina, and S. G. Georgieva A retrocopy of a gene can functionally displace the source gene in evolution Nucleic Acids Res., November 27, 2005; 33(20): 6654 - 6661. [Abstract] [Full Text] [PDF]
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C. F. Cullen, A. L. Brittle, T. Ito, and H. Ohkura The conserved kinase NHK-1 is essential for mitotic progression and unifying acentrosomal meiotic spindles in Drosophila melanogaster J. Cell Biol., November 21, 2005; 171(4): 593 - 602. [Abstract] [Full Text] [PDF]
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N. T. Takaesu, E. Herbig, D. Zhitomersky, M. B. O'Connor, and S. J. Newfeld DNA-binding domain mutations in SMAD genes yield dominant-negative proteins or a neomorphic protein that can activate WG target genes in Drosophila Development, November 1, 2005; 132(21): 4883 - 4894. [Abstract] [Full Text] [PDF]
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D. Dorsett, J. C. Eissenberg, Z. Misulovin, A. Martens, B. Redding, and K. McKim Effects of sister chromatid cohesion proteins on cut gene expression during wing development in Drosophila Development, November 1, 2005; 132(21): 4743 - 4753. [Abstract] [Full Text] [PDF]
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P. D. Karp, C. A. Ouzounis, C. Moore-Kochlacs, L. Goldovsky, P. Kaipa, D. Ahren, S. Tsoka, N. Darzentas, V. Kunin, and N. Lopez-Bigas Expansion of the BioCyc collection of pathway/genome databases to 160 genomes Nucleic Acids Res., October 24, 2005; 33(19): 6083 - 6089. [Abstract] [Full Text] [PDF]
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M. R. Bogwitz, H. Chung, L. Magoc, S. Rigby, W. Wong, M. O'Keefe, J. A. McKenzie, P. Batterham, and P. J. Daborn Cyp12a4 confers lufenuron resistance in a natural population of Drosophila melanogaster PNAS, September 6, 2005; 102(36): 12807 - 12812. [Abstract] [Full Text] [PDF]
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