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Nucleic Acids Research 2005 33(Database Issue):D413-D417; doi:10.1093/nar/gki037
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Nucleic Acids Research, 2005, Vol. 33, Database issue D413-D417
© 2005, the authors
Nucleic Acids Research, Vol. 33, Database issue © Oxford University Press 2005; all rights reserved

3did: interacting protein domains of known three-dimensional structure

Amelie Stein1, Robert B. Russell1,2 and Patrick Aloy1,*

1 EMBL, Meyerhofstrasse 1, 69117 Heidelberg, Germany and 2 EMBL, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton Hall, Cambridge CB10 1SD, UK

* To whom correspondence should be addressed. Tel: +49 6221 387 305; Fax: +49 6221 387 517; Email: aloy{at}embl.de

Received July 22, 2004; Revised and Accepted September 23, 2004

The database of 3D Interacting Domains (3did) is a collection of domain–domain interactions in proteins for which high-resolution three-dimensional structures are known. 3did exploits structural information to provide critical molecular details necessary for understanding how interactions occur. It also offers an overview of how similar in structure are interactions between different members of the same protein family. The database also contains Gene Ontology-based functional annotations and interactions between yeast proteins from large-scale interaction discovery studies. A web-based tool to query 3did is available at http://3did.embl.de.

The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use permissions, please contact journals.permissions{at}oupjournals.org.


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