Nucleic Acids Research, 2005, Vol. 33, Database issue D54-D58
© 2005, the authors
Nucleic Acids Research, Vol. 33, Database issue © Oxford University Press 2005; all rights reserved
Entrez Gene: gene-centered information at NCBI
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Room 5AS.13B, 45 Center Drive, Bethesda, MD 20892-6510, USA
* To whom correspondence should be addressed. Tel: +1 301 435 5950; Fax: +1 301 480 2918; Email: maglott{at}ncbi.nlm.nih.gov
Received September 15, 2004; Accepted September 22, 2004
Entrez Gene (www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene) is NCBI's database for gene-specific information. It does not include all known or predicted genes; instead Entrez Gene focuses on the genomes that have been completely sequenced, that have an active research community to contribute gene-specific information, or that are scheduled for intense sequence analysis. The content of Entrez Gene represents the result of curation and automated integration of data from NCBI's Reference Sequence project (RefSeq), from collaborating model organism databases, and from many other databases available from NCBI. Records are assigned unique, stable and tracked integers as identifiers. The content (nomenclature, map location, gene products and their attributes, markers, phenotypes, and links to citations, sequences, variation details, maps, expression, homologs, protein domains and external databases) is updated as new information becomes available. Entrez Gene is a step forward from NCBI's LocusLink, with both a major increase in taxonomic scope and improved access through the many tools associated with NCBI Entrez.
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use permissions, please contact journals.permissions{at}oupjournals.org.
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
I. Steinfeld, R. Navon, D. Ardigo, I. Zavaroni, and Z. Yakhini Clinically driven semi-supervised class discovery in gene expression data Bioinformatics, August 15, 2008; 24(16): i90 - i97. [Abstract] [PDF] |
||||
![]() |
Z. Hu, E. S. Snitkin, and C. DeLisi VisANT: an integrative framework for networks in systems biology Brief Bioinform, July 1, 2008; 9(4): 317 - 325. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Dittrich, I. Birschmann, S. Mietner, A. Sickmann, U. Walter, and T. Dandekar Platelet Protein Interactions: Map, Signaling Components, and Phosphorylation Groundstate Arterioscler. Thromb. Vasc. Biol., July 1, 2008; 28(7): 1326 - 1331. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Tsesmetzis, M. Couchman, J. Higgins, A. Smith, J. H. Doonan, G. J. Seifert, E. E. Schmidt, I. Vastrik, E. Birney, G. Wu, et al. Arabidopsis Reactome: A Foundation Knowledgebase for Plant Systems Biology PLANT CELL, June 1, 2008; 20(6): 1426 - 1436. [Full Text] [PDF] |
||||
![]() |
M. Z. de Pina, H. Vazquez-Meza, J. P. Pardo, J. L. Rendon, R. Villalobos-Molina, H. Riveros-Rosas, and E. Pina Signaling the Signal, Cyclic AMP-dependent Protein Kinase Inhibition by Insulin-formed H2O2 and Reactivation by Thioredoxin J. Biol. Chem., May 2, 2008; 283(18): 12373 - 12386. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. C. Ziesel, M. A. Chrenek, and P. W. Wong MultiPriDe: automated batch development of quantitative real-time PCR primers Nucleic Acids Res., May 1, 2008; 36(9): 3095 - 3100. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. F. Sinner, A. Pfeufer, M. Akyol, B.-M. Beckmann, M. Hinterseer, A. Wacker, S. Perz, W. Sauter, T. Illig, M. Nabauer, et al. The non-synonymous coding IKr-channel variant KCNH2-K897T is associated with atrial fibrillation: results from a systematic candidate gene-based analysis of KCNH2 (HERG) Eur. Heart J., April 1, 2008; 29(7): 907 - 914. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Ansong, S. O. Purvine, J. N. Adkins, M. S. Lipton, and R. D. Smith Proteogenomics: needs and roles to be filled by proteomics in genome annotation Brief Funct Genomic Proteomic, March 10, 2008; (2008) eln010v1. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. O. Barrera, Z. Li, A. D. Smith, K. C. Arden, W. K. Cavenee, M. Q. Zhang, R. D. Green, and B. Ren Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs Genome Res., January 1, 2008; 18(1): 46 - 59. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. F. Murphy, G. J. Hooiveld, M. Muller, R. A. Calogero, and K. D. Cashman Conjugated Linoleic Acid Alters Global Gene Expression in Human Intestinal-Like Caco-2 Cells in an Isomer-Specific Manner J. Nutr., November 1, 2007; 137(11): 2359 - 2365. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. Zintzaras, G. Kitsios, D. Kent, N. J. Camp, L. Atwood, P. N. Hopkins, and S. C. Hunt Genome-Wide Scans Meta-Analysis for Pulse Pressure Hypertension, September 1, 2007; 50(3): 557 - 564. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. W. Tullai, M. E. Schaffer, S. Mullenbrock, G. Sholder, S. Kasif, and G. M. Cooper Immediate-Early and Delayed Primary Response Genes Are Distinct in Function and Genomic Architecture J. Biol. Chem., August 17, 2007; 282(33): 23981 - 23995. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Meehl, S. Herbert, F. Gotz, and A. Cheung Interaction of the GraRS Two-Component System with the VraFG ABC Transporter To Support Vancomycin-Intermediate Resistance in Staphylococcus aureus Antimicrob. Agents Chemother., August 1, 2007; 51(8): 2679 - 2689. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Osada Inference of Expression-Dependent Negative Selection Based on Polymorphism and Divergence in the Human Genome Mol. Biol. Evol., August 1, 2007; 24(8): 1622 - 1626. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. Lee, T. Hong, S. J. Byun, T. Woo, and Y. J. Choi ESTpass: a web-based server for processing and annotating expressed sequence tag (EST) sequences Nucleic Acids Res., July 13, 2007; 35(suppl_2): W159 - W162. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. W. Huang, B. T. Sherman, Q. Tan, J. Kir, D. Liu, D. Bryant, Y. Guo, R. Stephens, M. W. Baseler, H. C. Lane, et al. DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists Nucleic Acids Res., July 13, 2007; 35(suppl_2): W169 - W175. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. A. Baumgartner Jr, K. B. Cohen, L. M. Fox, G. Acquaah-Mensah, and L. Hunter Manual curation is not sufficient for annotation of genomic databases Bioinformatics, July 1, 2007; 23(13): i41 - i48. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Sasidharan and C. Chothia The selection of acceptable protein mutations PNAS, June 12, 2007; 104(24): 10080 - 10085. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Johnson, O. Fletcher, C. Palles, M. Rudd, E. Webb, G. Sellick, I. dos Santos Silva, V. McCormack, L. Gibson, A. Fraser, et al. Counting potentially functional variants in BRCA1, BRCA2 and ATM predicts breast cancer susceptibility Hum. Mol. Genet., May 1, 2007; 16(9): 1051 - 1057. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. J. Gaulton, K. L. Mohlke, and T. J. Vision A computational system to select candidate genes for complex human traits Bioinformatics, May 1, 2007; 23(9): 1132 - 1140. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. H. Otu, K. Naxerova, K. Ho, H. Can, N. Nesbitt, T. A. Libermann, and S. J. Karp Restoration of Liver Mass after Injury Requires Proliferative and Not Embryonic Transcriptional Patterns J. Biol. Chem., April 13, 2007; 282(15): 11197 - 11204. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Schlicker, C. Huthmacher, F. Ramirez, T. Lengauer, and M. Albrecht Functional evaluation of domain domain interactions and human protein interaction networks Bioinformatics, April 1, 2007; 23(7): 859 - 865. [Abstract] [Full Text] [PDF] |
||||
![]() |
U. T. Shankavaram, W. C. Reinhold, S. Nishizuka, S. Major, D. Morita, K. K. Chary, M. A. Reimers, U. Scherf, A. Kahn, D. Dolginow, et al. Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study Mol. Cancer Ther., March 1, 2007; 6(3): 820 - 832. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. C. Duarte, S. A. Becker, N. Jamshidi, I. Thiele, M. L. Mo, T. D. Vo, R. Srivas, and B. O. Palsson Global reconstruction of the human metabolic network based on genomic and bibliomic data PNAS, February 6, 2007; 104(6): 1777 - 1782. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. Lee, T. Kim, S.-K. Kim, K. H. Lee, and D. Lee Patome: a database server for biological sequence annotation and analysis in issued patents and published patent applications Nucleic Acids Res., January 12, 2007; 35(suppl_1): D47 - D50. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Kim, A. V. Alekseyenko, M. Roy, and C. Lee The ASAP II database: analysis and comparative genomics of alternative splicing in 15 animal species Nucleic Acids Res., January 12, 2007; 35(suppl_1): D93 - D98. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Groth, N. Pavlova, I. Kalev, S. Tonov, G. Georgiev, H.-D. Pohlenz, and B. Weiss PhenomicDB: a new cross-species genotype/phenotype resource Nucleic Acids Res., January 12, 2007; 35(suppl_1): D696 - D699. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. M. Mazzarelli, J. Brestelli, R. K. Gorski, J. Liu, E. Manduchi, D. F. Pinney, J. Schug, P. White, K. H. Kaestner, and C. J. Stoeckert Jr EPConDB: a web resource for gene expression related to pancreatic development, beta-cell function and diabetes Nucleic Acids Res., January 12, 2007; 35(suppl_1): D751 - D755. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. M. Smith, J. H. Finger, T. F. Hayamizu, I. J. McCright, J. T. Eppig, J. A. Kadin, J. E. Richardson, and M. Ringwald The mouse Gene Expression Database (GXD): 2007 update Nucleic Acids Res., January 12, 2007; 35(suppl_1): D618 - D623. [Abstract] [Full Text] [PDF] |
||||
![]() |
Q. Ren, K. Chen, and I. T. Paulsen TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels Nucleic Acids Res., January 12, 2007; 35(suppl_1): D274 - D279. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. N. Twigger, M. Shimoyama, S. Bromberg, A. E. Kwitek, H. J. Jacob, and the RGD Team The Rat Genome Database, update 2007--Easing the path from disease to data and back again Nucleic Acids Res., January 12, 2007; 35(suppl_1): D658 - D662. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. A. Eyre, M. W. Wright, M. J. Lush, and E. A. Bruford HCOP: a searchable database of human orthology predictions Brief Bioinform, January 1, 2007; 8(1): 2 - 5. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. L. Andersen, C. Wiuf, M. Kruhoffer, M. Korsgaard, S. Laurberg, and T. F. Orntoft Frequent occurrence of uniparental disomy in colorectal cancer Carcinogenesis, January 1, 2007; 28(1): 38 - 48. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Draghici, S. Sellamuthu, and P. Khatri Babel's tower revisited: a universal resource for cross-referencing across annotation databases Bioinformatics, December 1, 2006; 22(23): 2934 - 2939. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. L. Webb, M. F. Rudd, G. S. Sellick, R. El Galta, L. Bethke, W. Wood, O. Fletcher, S. Penegar, L. Withey, M. Qureshi, et al. Search for low penetrance alleles for colorectal cancer through a scan of 1467 non-synonymous SNPs in 2575 cases and 2707 controls with validation by kin-cohort analysis of 14 704 first-degree relatives Hum. Mol. Genet., November 1, 2006; 15(21): 3263 - 3271. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. R. Grimes, T. Q. Wen, M. Mewissen, R. M. Baxter, S. Moodie, J. S. Beattie, and P. Ghazal PDQ Wizard: automated prioritization and characterization of gene and protein lists using biomedical literature Bioinformatics, August 15, 2006; 22(16): 2055 - 2057. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Pang, A. Lin, M. Holford, B. E. Enerson, B. Lu, M. P. Lawton, E. Floyd, and H. Zhao Pathway analysis using random forests classification and regression Bioinformatics, August 15, 2006; 22(16): 2028 - 2036. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. M. Rodriguez, M. A. Glozak, Y. Ma, and W. D. Cress Bok, Bcl-2-related Ovarian Killer, Is Cell Cycle-regulated and Sensitizes to Stress-induced Apoptosis J. Biol. Chem., August 11, 2006; 281(32): 22729 - 22735. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. J. Mattingly, M. C. Rosenstein, A. P. Davis, G. T. Colby, J. N. Forrest Jr, and J. L. Boyer The Comparative Toxicogenomics Database: A Cross-Species Resource for Building Chemical-Gene Interaction Networks Toxicol. Sci., August 1, 2006; 92(2): 587 - 595. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. F. Rudd, G. S. Sellick, E. L. Webb, D. Catovsky, and R. S. Houlston Variants in the ATM-BRCA2-CHEK2 axis predispose to chronic lymphocytic leukemia Blood, July 15, 2006; 108(2): 638 - 644. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. J. Donaldson and B. Gottgens TFBScluster web server for the identification of mammalian composite regulatory elements. Nucleic Acids Res., July 1, 2006; 34(Web Server issue): W524 - W528. [Abstract] [Full Text] [PDF] |
||||
![]() |
V. Shepelev and A. Fedorov Advances in the Exon-Intron Database (EID) Brief Bioinform, June 1, 2006; 7(2): 178 - 185. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. F. Rudd, E. L. Webb, A. Matakidou, G. S. Sellick, R. D. Williams, H. Bridle, T. Eisen, R. S. Houlston, and the GELCAPS Consortium Variants in the GH-IGF axis confer susceptibilityto lung cancer. Genome Res., June 1, 2006; 16(6): 693 - 701. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Muramatsu and M. Suwa Statistical analysis and prediction of functional residues effective for GPCR-G-protein coupling selectivity Protein Eng. Des. Sel., June 1, 2006; 19(6): 277 - 283. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Hearle, V. Schumacher, F. H. Menko, S. Olschwang, L. A. Boardman, J. J.P. Gille, J. J. Keller, A. M. Westerman, R. J. Scott, W. Lim, et al. Frequency and spectrum of cancers in the peutz-jeghers syndrome. Clin. Cancer Res., May 15, 2006; 12(10): 3209 - 3215. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Olivero, T. Ruggiero, S. Saviozzi, A. Rasola, N. Coltella, S. Crispi, F. Di Cunto, R. Calogero, and M. F. Di Renzo Genes regulated by hepatocyte growth factor as targets to sensitize ovarian cancer cells to cisplatin Mol. Cancer Ther., May 1, 2006; 5(5): 1126 - 1135. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. J. Rampil, D. H. Moller, and A. H. Bell Isoflurane modulates genomic expression in rat amygdala. Anesth. Analg., May 1, 2006; 102(5): 1431 - 1438. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. B. Montgomery, O. L. Griffith, M. C. Sleumer, C. M. Bergman, M. Bilenky, E. D. Pleasance, Y. Prychyna, X. Zhang, and S. J. M. Jones ORegAnno: an open access database and curation system for literature-derived promoters, transcription factor binding sites and regulatory variation Bioinformatics, March 1, 2006; 22(5): 637 - 640. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Basu, E. Bremer, C. Zhou, and D. F. Bogenhagen MiGenes: a searchable interspecies database of mitochondrial proteins curated using gene ontology annotation Bioinformatics, February 15, 2006; 22(4): 485 - 492. [Abstract] [Full Text] [PDF] |
||||
![]() |
U. Dogrusoz, E. Z. Erson, E. Giral, E. Demir, O. Babur, A. Cetintas, and R. Colak PATIKAweb: a Web interface for analyzing biological pathways through advanced querying and visualization Bioinformatics, February 1, 2006; 22(3): 374 - 375. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Chen, N. Huang, and Z. Sun SubLoc: a server/client suite for protein subcellular location based on SOAP Bioinformatics, February 1, 2006; 22(3): 376 - 377. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Kimura, A. Wakamatsu, Y. Suzuki, T. Ota, T. Nishikawa, R. Yamashita, J.-i. Yamamoto, M. Sekine, K. Tsuritani, H. Wakaguri, et al. Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes Genome Res., January 1, 2006; 16(1): 55 - 65. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Kim, P. Kim, S. Nam, S. Shin, and S. Lee ChimerDB--a knowledgebase for fusion sequences Nucleic Acids Res., January 1, 2006; 34(suppl_1): D21 - D24. [Abstract] [Full Text] [PDF] |
||||
![]() |
V. Matys, O. V. Kel-Margoulis, E. Fricke, I. Liebich, S. Land, A. Barre-Dirrie, I. Reuter, D. Chekmenev, M. Krull, K. Hornischer, et al. TRANSFAC(R) and its module TRANSCompel(R): transcriptional gene regulation in eukaryotes Nucleic Acids Res., January 1, 2006; 34(suppl_1): D108 - D110. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Wu, J. Wang, C. Liu, Y. Zhang, B. Shi, X. Zhu, Z. Zhang, G. Skogerbo, L. Chen, H. Lu, et al. NPInter: the noncoding RNAs and protein related biomacromolecules interaction database Nucleic Acids Res., January 1, 2006; 34(suppl_1): D150 - D152. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. L. Wheeler, T. Barrett, D. A. Benson, S. H. Bryant, K. Canese, V. Chetvernin, D. M. Church, M. DiCuccio, R. Edgar, S. Federhen, et al. Database resources of the National Center for Biotechnology Information Nucleic Acids Res., January 1, 2006; 34(suppl_1): D173 - D180. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. L. Fink, R. N. Aturaliya, M. J. Davis, F. Zhang, K. Hanson, M. S. Teasdale, C. Kai, J. Kawai, P. Carninci, Y. Hayashizaki, et al. LOCATE: a mouse protein subcellular localization database Nucleic Acids Res., January 1, 2006; 34(suppl_1): D213 - D217. [Abstract] [Full Text] [PDF] |
||||





















