Nucleic Acids Research, 2005, Vol. 33, Database issue D588-D592
© 2005, the authors
Nucleic Acids Research, Vol. 33, Database issue © Oxford University Press 2005; all rights reserved
MetaRouter: bioinformatics for bioremediation
Department of Biological Sciences, Structural Bioinformatics Group, Biochemistry Building, Imperial College, London SW7 2AZ, UK, 1 bioALMA, Centro Empresarial Euronova, Ronda de Poniente, 4, 2nd floor, Unit C-D, 28760 Tres Cantos, Madrid, Spain and 2 National Center for Biotechnology, Cantoblanco, 28049 Madrid, Spain
* To whom correspondence should be addressed. Tel: +44 0 20 7594 5737; Fax: +44 0 20 7594 5789; Email: f.pazos{at}imperial.ac.uk
Received August 14, 2004; Revised and Accepted October 5, 2004
Bioremediation, the exploitation of biological catalysts (mostly microorganisms) for removing pollutants from the environment, requires the integration of huge amounts of data from different sources. We have developed MetaRouter, a system for maintaining heterogeneous information related to bioremediation in a framework that allows its query, administration and mining (application of methods for extracting new knowledge). MetaRouter is an application intended for laboratories working in biodegradation and bioremediation, which need to maintain and consult public and private data, linked internally and with external databases, and to extract new information from it. Among the data-mining features is a program included for locating biodegradative pathways for chemical compounds according to a given set of constraints and requirements. The integration of biodegradation information with the corresponding protein and genome data provides a suitable framework for studying the global properties of the bioremediation network. The system can be accessed and administrated through a web interface. The full-featured system (except administration facilities) is freely available at http://pdg.cnb.uam.es/MetaRouter. Additional material: http://www.pdg.cnb.uam.es/biodeg_net/MetaRouter.
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