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Nucleic Acids Research 2005 33(Web Server Issue):W468-W470; doi:10.1093/nar/gki463
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© The Author 2005. Published by Oxford University Press. All rights reserved
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Article

Integrating protein annotation resources through the Distributed Annotation System

Páll Ísólfur Ólason*

Center for Biological Sequence Analysis BioCentrum-DTU Building 208 Technical University of Denmark DK-2800 Lyngby, Denmark

*Tel: +45 45 25 24 71; Fax: +45 45 93 15 85; Email: pall{at}cbs.dtu.dk

Received February 14, 2005. Revised April 13, 2005. Accepted April 13, 2005.

Using the Distributed Annotation System (DAS) we have created a protein annotation resource available at our web page: http://www.cbs.dtu.dk, as a part of the BioSapiens Network of Excellence EU FP6 project. The DAS protocol allows us to gather layers of annotation data for a given sequence and thereby gain an overview of the sequence's features. A user-friendly graphical client has also been developed (http://www.cbs.dtu.dk/cgi-bin/das), which demonstrates the possibility of integrating DAS annotation data from multiple sources into a simple graphical view. The client displays protein feature annotations from the Center for Biological Sequence Analysis as well as from the BioSapiens reference UniProt server (http://www.ebi.ac.uk/das-srv/uniprot/das) at the European Bioinformatics Institute. Other DAS data sources for protein annotation will be added as they become available.


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