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Nucleic Acids Research 2006 34(Web Server issue):W293-W297; doi:10.1093/nar/gkl031
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© The Author 2006. Published by Oxford University Press. All rights reserved
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oxfordjournals.org

Article

WEGO: a web tool for plotting GO annotations

Jia Ye1, Lin Fang2, Hongkun Zheng2, Yong Zhang2,3, Jie Chen2, Zengjin Zhang2, Jing Wang2, Shengting Li2,4, Ruiqiang Li2,5, Lars Bolund2,4 and Jun Wang1–,5,*

1 James D. Watson Institute of Genome Sciences of Zhejiang University Hangzhou 310008, China 2 Beijing Genomics Institute Beijing 101300, China 3 College of Life Sciences, Peking University Beijing 100871, China 4 The Institute of Human Genetics, University of Aarhus DK-8000 Aarhus C, Denmark 5 Department of Biochemistry and Molecular Biology, University of Southern Denmark DK-5230, Odense M, Denmark

*To whom correspondence should be addressed. Tel: +86 10 80491664; Fax: +86 10 80498676; Email: wangj{at}genomics.org.cn

Correspondence may also be addressed to Lars Bolund. Tel: +45 89421675; Fax: +45 86123173; Email: bolund{at}humgen.au.dk

Received October 21, 2005. Revised November 29, 2005. Accepted November 29, 2005.

Unified, structured vocabularies and classifications freely provided by the Gene Ontology (GO) Consortium are widely accepted in most of the large scale gene annotation projects. Consequently, many tools have been created for use with the GO ontologies. WEGO (Web Gene Ontology Annotation Plot) is a simple but useful tool for visualizing, comparing and plotting GO annotation results. Different from other commercial software for creating chart, WEGO is designed to deal with the directed acyclic graph structure of GO to facilitate histogram creation of GO annotation results. WEGO has been used widely in many important biological research projects, such as the rice genome project and the silkworm genome project. It has become one of the daily tools for downstream gene annotation analysis, especially when performing comparative genomics tasks. WEGO, along with the two other tools, namely External to GO Query and GO Archive Query, are freely available for all users at http://wego.genomics.org.cn. There are two available mirror sites at http://wego2.genomics.org.cn and http://wego.genomics.com.cn. Any suggestions are welcome at wego{at}genomics.org.cn.

The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors


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