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Nucleic Acids Research 2007 35(Database issue):D269-D270; doi:10.1093/nar/gkl891
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Nucleic Acids Research, 2007, Vol. 35, Database issue D269-D270
© 2006 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Articles

REBASE—enzymes and genes for DNA restriction and modification

Richard J. Roberts*, Tamas Vincze, Janos Posfai and Dana Macelis

New England Biolabs, Inc. 240 County Road, Ipswich, MA 01938, USA

*To whom correspondence should be addressed. Tel: +1 978 380 7405; Fax: +1 978 380 7406; Email: roberts{at}neb.com

Received September 11, 2006. Accepted October 9, 2006.

REBASE is a comprehensive database of information about restriction enzymes, DNA methyltransferases and related proteins involved in the biological process of restriction-modification. It contains fully referenced information about recognition and cleavage sites, isoschizomers, neoschizomers, commercial availability, methylation sensitivity, crystal and sequence data. Experimentally characterized homing endonucleases are also included. All newly sequenced genomes are analyzed for the presence of putative restriction systems and these data are included within the REBASE. The contents or REBASE may be browsed from the web (http://rebase.neb.com/rebase/rebase.ftp.html) and selected compilations can be downloaded by ftp (ftp.neb.com). Additionally, monthly updates can be requested via email.


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