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Nucleic Acids Research Advance Access originally published online on November 29, 2006
Nucleic Acids Research 2007 35(Database issue):D572-D574; doi:10.1093/nar/gkl950
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Nucleic Acids Research, 2007, Vol. 35, Database issue D572-D574
© 2006 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Articles

MINT: the Molecular INTeraction database

Andrew Chatr-aryamontri, Arnaud Ceol, Luisa Montecchi Palazzi, Giuliano Nardelli, Maria Victoria Schneider, Luisa Castagnoli and Gianni Cesareni*

Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy

*To whom correspondence should be addressed. Tel: +39 067 2594315; Fax: +39 062 023500; Email: Cesareni{at}uniroma2.it

Received September 15, 2006. Revised October 18, 2006. Accepted October 20, 2006.

The Molecular INTeraction database (MINT, http://mint.bio.uniroma2.it/mint/) aims at storing, in a structured format, information about molecular interactions (MIs) by extracting experimental details from work published in peer-reviewed journals. At present the MINT team focuses the curation work on physical interactions between proteins. Genetic or computationally inferred interactions are not included in the database. Over the past four years MINT has undergone extensive revision. The new version of MINT is based on a completely remodeled database structure, which offers more efficient data exploration and analysis, and is characterized by entries with a richer annotation. Over the past few years the number of curated physical interactions has soared to over 95 000. The whole dataset can be freely accessed online in both interactive and batch modes through web-based interfaces and an FTP server. MINT now includes, as an integrated addition, HomoMINT, a database of interactions between human proteins inferred from experiments with ortholog proteins in model organisms (http://mint.bio.uniroma2.it/mint/).

The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors


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