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Nucleic Acids Research Advance Access originally published online on October 16, 2007
Nucleic Acids Research 2008 36(Database issue):D298-D302; doi:10.1093/nar/gkm768
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Nucleic Acids Research, 2008, Vol. 36, Database issue D298-D302
© 2007 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Articles

ChromDB: The Chromatin Database

Karla Gendler, Tara Paulsen and Carolyn Napoli*

BIO5 Institute, University of Arizona, Tucson, AZ 85719, USA

* To whom correspondence should be addressed. Tel: +1 520 626 3824; Fax: +1 520 626 4824; Email: cnapoli{at}email.arizona.edu

Received August 16, 2007. Revised September 4, 2007. Accepted September 11, 2007.

The ChromDB website (http://www.chromdb.org) displays chromatin-associated proteins, including RNAi-associated proteins, for a broad range of organisms. Our primary focus is to display sets of highly curated plant genes predicted to encode proteins associated with chromatin remodeling. Our intent is to make this intensively curated sequence information available to the research and teaching communities in support of comparative analyses toward understanding the chromatin proteome in plants, especially in important crop species such as corn and rice. Model animal and fungal proteins are included in the database to facilitate a complete, comparative analysis of the chromatin proteome and to make the database applicable to all chromatin researchers and educators. Chromatin biology and chromatin remodeling are complex processes involving a multitude of proteins that regulate the dynamic changes in chromatin structure which either repress or activate transcription. We strive to organize ChromDB data in a straightforward and comparative manner to help users understand the complement of proteins involved in packaging DNA into chromatin.


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