Nucleic Acids Research Advance Access originally published online on October 12, 2007
Nucleic Acids Research 2008 36(Database issue):D966-D969; doi:10.1093/nar/gkm841
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Nucleic Acids Research, 2008, Vol. 36, Database issue D966-D969
© 2007 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
This article appears in the following Nucleic Acids Research issue: Database issue [View the issue table of contents]
Articles |
PlantTFDB: a comprehensive plant transcription factor database
College of Life Sciences, National Laboratory of Protein Engineering and Plant Genetic Engineering, Center for Bioinformatics, Peking University, Beijing 100871, China
*To whom correspondence should be addressed. Tel: 86-10-6275-7281; Fax: 86-10-6275-9001; Email: luojc{at}pku.edu.cn Correspondence may also be addressed to Kun He. Email: hek{at}mail.cbi.pku.edu.cn
Received August 14, 2007. Revised September 22, 2007. Accepted September 25, 2007.
Transcription factors (TFs) play key roles in controlling gene expression. Systematic identification and annotation of TFs, followed by construction of TF databases may serve as useful resources for studying the function and evolution of transcription factors. We developed a comprehensive plant transcription factor database PlantTFDB (http://planttfdb.cbi.pku.edu.cn), which contains 26 402 TFs predicted from 22 species, including five model organisms with available whole genome sequence and 17 plants with available EST sequences. To provide comprehensive information for those putative TFs, we made extensive annotation at both family and gene levels. A brief introduction and key references were presented for each family. Functional domain information and cross-references to various well-known public databases were available for each identified TF. In addition, we predicted putative orthologs of those TFs among the 22 species. PlantTFDB has a simple interface to allow users to search the database by IDs or free texts, to make sequence similarity search against TFs of all or individual species, and to download TF sequences for local analysis.
The authors wish to be known that, in their opinion, the first two authors should be regarded as joint First Authors.
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