Nucleic Acids Research Advance Access originally published online on September 29, 2008
Nucleic Acids Research 2009 37(Database issue):D526-D530; doi:10.1093/nar/gkn631
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Nucleic Acids Research, 2009, Vol. 37, Database issue D526-D530
© 2008 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
This article appears in the following Nucleic Acids Research issue: Database issue [View the issue table of contents]
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GiardiaDB and TrichDB: integrated genomic resources for the eukaryotic protist pathogens Giardia lamblia and Trichomonas vaginalis
1Center for Tropical & Emerging Global Diseases, University of Georgia, Athens, GA 30602, 2Penn Center for Bioinformatics, University of Pennsylvania, Philadelphia, PA 19104, 3Department of Medical Parasitology, New York University Langone Medical Center, New York, NY 10010, 4Center for Applied Genetic Technologies, University of Georgia, Athens, GA 30602, 5School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, 6Department of Genetics, 7Department of Computer Science, University of Georgia, Athens, GA 30602, 8Josephine Bay Paul Center [for Comparative Molecular Biology and Evolution], Marine Biological Laboratory, Woods Hole, MA 02543 and 9Department of Biology, University of Pennsylvania, Philadelphia, PA 19104 USA
*To whom correspondence should be addressed. Tel: +1 215 746 7019; Fax: +1 215 573 3111; Email: oharb{at}pcbi.upenn.edu
Correspondence may also be addressed to Brian P. Brunk. Tel: +1 215 573 3118; Fax: +1 215 573 3111; Email: brunkb{at}pcbi.upenn.edu; Jessica C. Kissinger. Tel: +1 706 542 6562; Fax: +1 706 542 3582; Email: jkissing{at}uga.edu; David S. Roos. Tel: +1 215 898 2118; Fax: +1 215 746 6697; Email: droos{at}sas.upenn.edu; Christian J. Stoeckert. Tel: +1 215 573 4409; Fax: +1 215 573 3111; Email: stoeckrt{at}pcbi.upenn.edu
Received August 15, 2008. Accepted September 14, 2008.
GiardiaDB (http://GiardiaDB.org) and TrichDB (http://TrichDB.org) house the genome databases for Giardia lamblia and Trichomonas vaginalis, respectively, and represent the latest additions to the EuPathDB (http://EuPathDB.org) family of functional genomic databases. GiardiaDB and TrichDB employ the same framework as other EuPathDB sites (CryptoDB, PlasmoDB and ToxoDB), supporting fully integrated and searchable databases. Genomic-scale data available via these resources may be queried based on BLAST searches, annotation keywords and gene ID searches, GO terms, sequence motifs and other protein characteristics. Functional queries may also be formulated, based on transcript and protein expression data from a variety of platforms. Phylogenetic relationships may also be interrogated. The ability to combine the results from independent queries, and to store queries and query results for future use facilitates complex, genome-wide mining of functional genomic data.
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