Skip Navigation


Nucleic Acids Research Advance Access originally published online on November 3, 2008
Nucleic Acids Research 2009 37(Database issue):D619-D622; doi:10.1093/nar/gkn863
This Article
Right arrow Full Text Freely available
Right arrow Print PDF (5053K) Freely available
Right arrow Screen PDF (607K) Freely available
Right arrowOA All Versions of this Article:
37/suppl_1/D619    most recent
gkn863v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Matthews, L.
Right arrow Articles by D’Eustachio, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Matthews, L.
Right arrow Articles by D’Eustachio, P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 2009, Vol. 37, Database issue D619-D622
© 2008 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

This article appears in the following Nucleic Acids Research issue: Database issue [View the issue table of contents]

Articles

Reactome knowledgebase of human biological pathways and processes

Lisa Matthews1, Gopal Gopinath1, Marc Gillespie1,2, Michael Caudy1, David Croft3, Bernard de Bono3, Phani Garapati3, Jill Hemish1, Henning Hermjakob3, Bijay Jassal3, Alex Kanapin1, Suzanna Lewis4, Shahana Mahajan5,6, Bruce May1, Esther Schmidt3, Imre Vastrik3, Guanming Wu1, Ewan Birney3, Lincoln Stein1,7 and Peter D’Eustachio1,6,*

1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, 2College of Pharmacy and Allied Health Professions, St. John's University, Queens, NY 11439, USA, 3European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK, 4Lawrence Berkeley National Laboratory, Berkeley, CA 94720, 5Hunter College, New York, NY 10010, 6NYU School of Medicine, New York, NY 10016, USA and 7Ontario Institute for Cancer Research, Toronto, ON, Canada M5G0A3

*To whom correspondence should be addressed. Tel: +1 212 263 5779; Fax: +1 212 263 8166; Email: deustp01{at}med.nyu.edu

Received September 17, 2008. Revised October 14, 2008. Accepted October 16, 2008.

Reactome (http://www.reactome.org) is an expert-authored, peer-reviewed knowledgebase of human reactions and pathways that functions as a data mining resource and electronic textbook. Its current release includes 2975 human proteins, 2907 reactions and 4455 literature citations. A new entity-level pathway viewer and improved search and data mining tools facilitate searching and visualizing pathway data and the analysis of user-supplied high-throughput data sets. Reactome has increased its utility to the model organism communities with improved orthology prediction methods allowing pathway inference for 22 species and through collaborations to create manually curated Reactome pathway datasets for species including Arabidopsis, Oryza sativa (rice), Drosophila and Gallus gallus (chicken). Reactome's data content and software can all be freely used and redistributed under open source terms.

The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Nucleic Acids ResHome page
T. W. Harris, I. Antoshechkin, T. Bieri, D. Blasiar, J. Chan, W. J. Chen, N. De La Cruz, P. Davis, M. Duesbury, R. Fang, et al.
WormBase: a comprehensive resource for nematode research
Nucleic Acids Res., November 12, 2009; (2009) gkp952v1.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
J. A. Vizcaino, R. Cote, F. Reisinger, H. Barsnes, J. M. Foster, J. Rameseder, H. Hermjakob, and L. Martens
The Proteomics Identifications database: 2010 update
Nucleic Acids Res., November 11, 2009; (2009) gkp964v1.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
A. Ceol, A. Chatr Aryamontri, L. Licata, D. Peluso, L. Briganti, L. Perfetto, L. Castagnoli, and G. Cesareni
MINT, the molecular interaction database: 2009 update
Nucleic Acids Res., November 6, 2009; (2009) gkp983v1.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
J. L. Y. Koh, H. Ding, M. Costanzo, A. Baryshnikova, K. Toufighi, G. D. Bader, C. L. Myers, B. J. Andrews, and C. Boone
DRYGIN: a database of quantitative genetic interaction networks in yeast
Nucleic Acids Res., October 30, 2009; (2009) gkp820v1.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
L. Y. Geer, A. Marchler-Bauer, R. C. Geer, L. Han, J. He, S. He, C. Liu, W. Shi, and S. H. Bryant
The NCBI BioSystems database
Nucleic Acids Res., October 23, 2009; (2009) gkp858v1.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
P. de Matos, R. Alcantara, A. Dekker, M. Ennis, J. Hastings, K. Haug, I. Spiteri, S. Turner, and C. Steinbeck
Chemical Entities of Biological Interest: an update
Nucleic Acids Res., October 23, 2009; (2009) gkp886v1.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
B. Aranda, P. Achuthan, Y. Alam-Faruque, I. Armean, A. Bridge, C. Derow, M. Feuermann, A. T. Ghanbarian, S. Kerrien, J. Khadake, et al.
The IntAct molecular interaction database in 2010
Nucleic Acids Res., October 22, 2009; (2009) gkp878v1.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
D. Glez-Pena, G. Gomez-Lopez, D. G. Pisano, and F. Fdez-Riverola
WhichGenes: a web-based tool for gathering, building, storing and exporting gene sets with application in gene set enrichment analysis
Nucleic Acids Res., July 1, 2009; 37(suppl_2): W329 - W334.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
Y. Yoshida, Y. Makita, N. Heida, S. Asano, A. Matsushima, M. Ishii, Y. Mochizuki, H. Masuya, S. Wakana, N. Kobayashi, et al.
PosMed (Positional Medline): prioritizing genes with an artificial neural network comprising medical documents to accelerate positional cloning
Nucleic Acids Res., July 1, 2009; 37(suppl_2): W147 - W152.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.