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Nucleic Acids Research, 1977, Vol. 4, No. 4 1123-1134
© 1977

Articles

Sequence analysis of the 3' non-coding region of mouse immunoglobulin light chain messenger RNA

P.H. Hamlyn, S. Gillam{dagger}, M. Smith{dagger} and C. Milstein

{dagger}Dept. of Biochemistry, University of British Columbia Vancouver B.C., Canada V6T 1W6 MRC Laboratory of Molecular Biology Hills Road, Cambridge CB2 2QH, UK

Received March 16, 1977. Using an oligonucleotide d(pTl0-C-A) as primer, cDNA has been transcribed from the 3' non-coding region of mouse immunoglobulin light chain mRNA and sequenced by a modification1 of the ‘plus-minus’ gel method2. The sequence obtained has partially corrected and extended a previously obtained sequence3. The new data contains an unusual sequence in which a trlnucleotide is repeated seven times.


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