Skip Navigation

This Article
Right arrow Print PDF (303K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (53)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Hearst, J. E.
Right arrow Articles by Thiry, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hearst, J. E.
Right arrow Articles by Thiry, L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1977, Vol. 4, No. 5 1339-1348
© 1977

Articles

The photoinactivation of an RNA animal virus, vesicular stomatitis virus, with the aid of newly synthesized psoralen derivatives

John E. Hearst*,+ and Lise Thiry++

+Dep.Chem., University of California Berkeley, CA 94720, USA ++Dep. Virol., Institut Pasteur du Brabant Rue du Remorgueur 28,1040 Bruxelles, Belgique

Received January 7, 1977.

The newly synthesized psoralen derivatives, 4' hydroxy-methyl 4,5',8 trimethylpsoralen, 4' methoxymethyl 4,5',8 trimethylpsoralen, and 4' aminomethyl 4,5',8 trimethylpsoralen hydrochloride photoreact with the single-stranded RNA animal virus, Vesicular Stomatitis virus, VSV. This virus is inactivated 103 times more effectively by photoreaction with these compounds than when photoreacted with 4,5',8 trimethylpsoralen. Under these conditions the RNA virus remains more than 103 times less sensitive to inactivation by these new photoreagents than were two double-stranded DNA viruses, Herpes Simplex type 2 (HSV-2) and Vaccinia. Preliminary evidence for the generality of this result is discussed.

*In memeory of Jerome Vinograd, the stoic - my educator and friend.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 BloodHome page
J. L. Gajewski, V. V. Johnson, S. G. Sandler, A. Sayegh, and T. R. Klumpp
A review of transfusion practice before, during, and after hematopoietic progenitor cell transplantation
Blood, October 15, 2008; 112(8): 3036 - 3047.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Goel, D. Jain, K. J. Kaur, R. Kenoth, B. G. Maiya, M. J. Swamy, and D. M. Salunke
Functional Equality in the Absence of Structural Similarity. AN ADDED DIMENSION TO MOLECULAR MIMICRY
J. Biol. Chem., October 12, 2001; 276(42): 39277 - 39281.
[Abstract] [Full Text] [PDF]

Home page
 J. Histochem. Cytochem.Home page
K. Sames, Z. Halata, M. Jojovic, E. J. M. van Damme, W. J. Peumans, B. Delpech, B. Asmus, and U. Schumacher
Lectin and Proteoglycan Histochemistry of Feline Pacinian Corpuscles
J. Histochem. Cytochem., January 1, 2001; 49(1): 19 - 28.
[Abstract] [Full Text]

Home page
 GlycobiologyHome page
E. Garcia-Hernandez, R. A. Zubillaga, A. Rodriguez-Romero, and A. Hernandez-Arana
Stereochemical metrics of lectin-carbohydrate interactions: comparison with protein-protein interfaces
Glycobiology, October 1, 2000; 10(10): 993 - 1000.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
W. Cheng, E. Bullitt, L. Bhattacharyya, C. F. Brewer, and L. Makowski
Electron Microscopy and X-ray Diffraction Studies of Lotus tetragonolobus A Isolectin Cross-linked with a Divalent Lewisx Oligosaccharide, an Oncofetal Antigen
J. Biol. Chem., December 25, 1998; 273(52): 35016 - 35022.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
X. Lee, A. Thompson, Z. Zhang, H. Ton-that, J. Biesterfeldt, C. Ogata, L. Xu, R. A. Z. Johnston, and N. M. Young
Structure of the Complex of Maclura pomifera Agglutinin and the T-antigen Disaccharide, Galbeta 1,3GalNAc
J. Biol. Chem., March 13, 1998; 273(11): 6312 - 6318.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
S. Prusiner
Novel proteinaceous infectious particles cause scrapie
Science, April 9, 1982; 216(4542): 136 - 144.
[Abstract] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.