Skip Navigation

This Article
Right arrow Print PDF (1018K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (204)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Holbrook, S. R.
Right arrow Articles by Kim, S.-H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Holbrook, S. R.
Right arrow Articles by Kim, S.-H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1977, Vol. 4, No. 8 2811-2820
© 1977

Articles

RNA - ligand interactions:(I) magnesium binding sites in yeast tRNAPhe

Stephen R. Holbrook, Joel L. Sussman, R. Wade Warrant, George M. Church and Sung-Hou Kim

Department of Biochemistry, Duke University Medical Center Durham, NC 27710, USA

Received May 20, 1977. X-ray crystallographic studies indicate that there are at least four site-specifically bound hydrated Mg2+ ions, [Mg(H2O)n]2+, in yeast tRNAPhe. The size and the octahedral coordination geometry, rather than the charge, of [Mg(H2O)n]2+ appear to be the primary reasons for the specificity of magnesium ions in site-binding and in the stabilization of the tertiary structure of tRNA.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 RNAHome page
W. Huggins, T. Shapkina, and P. Wollenzien
Conformational energy and structure in canonical and noncanonical forms of tRNA determined by temperature analysis of the rate of s4U8 C13 photocrosslinking
RNA, November 1, 2007; 13(11): 2000 - 2011.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
K. L. Britton, P. J. Baker, M. Fisher, S. Ruzheinikov, D. J. Gilmour, M.-J. Bonete, J. Ferrer, C. Pire, J. Esclapez, and D. W. Rice
Analysis of protein solvent interactions in glucose dehydrogenase from the extreme halophile Haloferax mediterranei
PNAS, March 28, 2006; 103(13): 4846 - 4851.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
L. R. Stefan, R. Zhang, A. G. Levitan, D. K. Hendrix, S. E. Brenner, and S. R. Holbrook
MeRNA: a database of metal ion binding sites in RNA structures
Nucleic Acids Res., January 1, 2006; 34(suppl_1): D131 - D134.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
S. Thiyagarajan, S. S. Rajan, and N. Gautham
Cobalt hexammine induced tautomeric shift in Z-DNA: the structure of d(CGCGCA).d(TGCGCG) in two crystal forms
Nucleic Acids Res., November 8, 2004; 32(19): 5945 - 5953.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
H. D. Kim, G. U. Nienhaus, T. Ha, J. W. Orr, J. R. Williamson, and S. Chu
Mg2+-dependent conformational change of RNA studied by fluorescence correlation and FRET on immobilized single molecules
PNAS, April 2, 2002; 99(7): 4284 - 4289.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
T.-C. Kuo and D. L. Herrin
Quantitative studies of Mn2+-promoted specific and non-specific cleavages of a large RNA: Mn2+-GAAA ribozymes and the evolution of small ribozymes
Nucleic Acids Res., November 1, 2000; 28(21): 4197 - 4206.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
J. Li, W. Zheng, A. H. Kwon, and Y. Lu
In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme
Nucleic Acids Res., January 15, 2000; 28(2): 481 - 488.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
N. E. Mikkelsen, M. Brannvall, A. Virtanen, and L. A. Kirsebom
Inhibition of RNase P RNA cleavage by aminoglycosides
PNAS, May 25, 1999; 96(11): 6155 - 6160.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
J. H. Cate, A. R. Gooding, E. Podell, K. Zhou, B. L. Golden, C. E. Kundrot, T. R. Cech, and J. A. Doudna
Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing
Science, September 20, 1996; 273(5282): 1678 - 1685.
[Abstract] [Full Text]

Home page
 J. Biol. Chem.Home page
M. Matsuo, T. Yokogawa, K. Nishikawa, K. Watanabe, and N. Okada
Highly Specific and Efficient Cleavage of Squid tRNA[IMAGE] Catalyzed by Magnesium Ions
J. Biol. Chem., April 28, 1995; 270(17): 10097 - 10104.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
A. Pyle
Ribozymes: a distinct class of metalloenzymes
Science, August 6, 1993; 261(5122): 709 - 714.
[Abstract] [PDF]

Home page
 ScienceHome page
D. Celander and T. Cech
Visualizing the higher order folding of a catalytic RNA molecule
Science, January 25, 1991; 251(4992): 401 - 407.
[Abstract] [PDF]

Home page
 ScienceHome page
J. Latham and T. Cech
Defining the inside and outside of a catalytic RNA molecule
Science, July 21, 1989; 245(4915): 276 - 282.
[Abstract] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.