Skip Navigation

This Article
Right arrow Print PDF (385K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (38)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Noguchi, S.
Right arrow Articles by Nishimura, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Noguchi, S.
Right arrow Articles by Nishimura, S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1978, Vol. 5, No. 11 4215-4224
© 1978

Articles

Isolation of Q nucleoside precursor present in tRNA of an E.coli mutant and its characterization as 7-(cyano)-7-deazaguanosine

Shigeru Noguchi+, Ziro Yamaizumi+, Tadaaki Ohgi{dagger}, Toshio Goto{dagger}, Yukinobu Nishimura*, Yukinori Hirota* and Susumu Nishimura+

+Biology Division, National Cancer Center Research Institute Tokyo {dagger}Department of Agricultural Chemistry, Nagoya University Nagoya *National Institute of Genetics Mishima, Japan

Received September 21, 1978. One of the E. coli mutants selected for deficiency of modified nucleoside Q was found to contain an analogue of Q and normal guanosine in place of Q. The analogue of Q, designated as preQo, was isolated on a large scale from purified tRNATYr containing preQo. The structure of preQo was determined to be 7-(cyano)-7-deazaguanosine by comparison of its ultraviolet absorption spectra, thin-layer chromatographic mobility and mass spectrum with those of synthetic material.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Bacteriol.Home page
R. Gaur and U. Varshney
Genetic Analysis Identifies a Function for the queC (ybaX) Gene Product at an Initial Step in the Queuosine Biosynthetic Pathway in Escherichia coli
J. Bacteriol., October 15, 2005; 187(20): 6893 - 6901.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
S. G. Van Lanen, J. S. Reader, M. A. Swairjo, V. de Crecy-Lagard, B. Lee, and D. Iwata-Reuyl
From cyclohydrolase to oxidoreductase: Discovery of nitrile reductase activity in a common fold
PNAS, March 22, 2005; 102(12): 4264 - 4269.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Watanabe, M. Matsuo, S. Tanaka, H. Akimoto, S. Asahi, S. Nishimura, J. R. Katze, T. Hashizume, P. F. Crain, J. A. McCloskey, et al.
Biosynthesis of Archaeosine, a Novel Derivative of 7-Deazaguanosine Specific to Archaeal tRNA, Proceeds via a Pathway Involving Base Replacement on the tRNA Polynucleotide Chain
J. Biol. Chem., August 8, 1997; 272(32): 20146 - 20151.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.