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Nucleic Acids Research, 1978, Vol. 5, No. 11 4273-4282
© 1978

Articles

Characteristics of excision repair of pyrimidine dimers in eukaryotic cells as assayed with anti-dimer sera

J.J. Cornelis

Laboratoire de Biophysique et Radiobiologie, Université Libre de Bruxelles Rue des Chevaux 67, 1640 Rhode St.Genè;se, Belgium

Received August 29, 1978. An antiserum that recognizes the three types of pyrimidine dimers induced by UV-light in DNA was used to monitor their removal from eukaryotic cell nuclei.Cells able to excise dimers display a similar removal pattern:a fast process completed within a few hours leaving many dimers in the DNA.


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