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Nucleic Acids Research, 1980, Vol. 8, No. 11 2431-2438
© 1980

Articles

Nucleotide sequences at the termini of La Crosse virus RNAs

John F. Obijeski*, John McCauley and John J. Shekei

Division of Virology, National Institute for Medical Research Mill Hill, London, NW7 1AA, UK

Received April 11, 1980.

The 5' and 3'-terminal sequences of the three RNA molecules which make up the genome of La Crosse virus are reported. Fleven nucleotides at both the 5' and 3' termini of all three RNAs are conserved and complementary. In addition more extensive unique sequence complementarity is present in at least two of the three RNAs.

* Permanent address. Viral Exanthems Branch, Virology Division, Bureau of Laboratories, Center for Disease Control, U.S. Public Health Service, Department of Health, Education and Welfare, Atlanta, Georgia 30333, USA.


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