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Nucleic Acids Research, 1980, Vol. 8, No. 16 3673-3694
© 1980


MOLECULAR BIOLOGY

A mew computer method for the storage and manipulation of DNA gel reading data

R. Staden

MRC Laboratory of Molecular Biology Hills Road, Cambridge CB2 2QH, UK

Received June 16, 1980. This paper describes a new way of storing DNA gel reading data and an accompanying set of computer programs. These programs will perform all the manipulations that are required on data gained by the so-called ‘shotgun’ method of DNA sequencing. This system simplifies the computer processing involved with this sequencing method and also has the capability of being able at any time during a project to display, lined up in register, all the gel readings covering any section of the sequence.


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