Skip Navigation

This Article
Right arrow Print PDF (499K)
Right arrow An erratum has been published
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (45)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Gray, D. M.
Right arrow Articles by Hayes, F.N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gray, D. M.
Right arrow Articles by Hayes, F.N.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1980, Vol. 8, No. 16 3695-3708
© 1980

MOLECULAR BIOLOGY

Circular dichroism spectra show that repeating dinucleotide DNAs may form helices in which every other best is looped out

Donald M. Gray, Marilyn Vaughan, Robert L. Ratcliff and F.Newton Hayes*

Program in Molecular Biology, University of Texas at Dallas P.O. Box 688, Richardson, TX 75080 Genetics Group, Life Sciences Division, Los Alamos Scientific Laboratory, University of California Los Alamos, NM 87545, USA

Received May 12, 1980.

We have found that the CD spectrum of poly[d(C-T)] undergoes a marked change upon protonation, taking on the unmistakable features of the spectrum of poly[d(C)·d(C+)]. The acid poly[d(C-T)] structure appears to be one in which each of the T residues is individually looped out of a helix formed by stacked C·C+ base pairs. We also present data for poly[d(C-A)] and review data for the other four possible repeating DNA dinucleotide sequences. These data show that self-complexes in which up to 50% of the residues are extrahelical may be unexceptional.

*Deceased. A friend and colleague we greatly miss.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Biophys. JHome page
E. Cubero, F. J. Luque, and M. Orozco
Theoretical Study of the Hoogsteen-Watson-Crick Junctions in DNA
Biophys. J., February 1, 2006; 90(3): 1000 - 1008.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
F.-M. Chen and F. M. Chen
Acid-facilitated Supramolecular Assembly of G-quadruplexes in d(CGG)(4)
J. Biol. Chem., September 29, 1995; 270(39): 23090 - 23096.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
R. Roberts and D. Crothers
Stability and properties of double and triple helices: dramatic effects of RNA or DNA backbone composition
Science, November 27, 1992; 258(5087): 1463 - 1466.
[Abstract] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.