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Nucleic Acids Research, 1980, Vol. 8, No. 22 5333-5346
© 1980


MOLECULAR BIOLOGY

Mobile dispersed genetic element MDGI of Drosophila melanogaster: structural organization

Y.V. Ilyin, V.G. Chmeliauskate, E.V. Ananiev{dagger}, N.V. Lyubomirskaya, V.V. Kulguskin, A.A. Bayev, Jr. and G.P. Georgiev

Institute of Molecular Biology, USSR Academy of Sciences Vavilov street 32, Moscow B-334, USSR {dagger}Institute of Molecular Genetics, USSR Academy of Sciences Vavilov street 32, Moscow B-334, USSR

Received July 22, 1980. The whole-length mobile dispersed genetic element mdg1 has been cloned from D. melanogaster genome. It contains DNA fragments described earlier as Dm225 and Dm234. Mdg1 is 7.2 kb long and framed with two direct repeats of 300–400 base pairs each. Mdg1 family is represented by about 25 copies in the genome of flies and by 200 copies in the genome of cultured cell line 67J25D. Virtually all the copies in the genome of D. melanogaster have the same restriction map. Oligo(dA)-oligo(dT) regions were found within mdg1.


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