Skip Navigation

This Article
Right arrow Print PDF (888K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Jaskólski, M.
Right arrow Articles by Wiewiórowski, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jaskólski, M.
Right arrow Articles by Wiewiórowski, M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1981, Vol. 9, No. 20 5423-5442
© 1981

CHEMISTRY

Comparative structural analysis of cytidine, ethenocytidine, and their protonated salts. I. Crystal and molecular structure of ethenocytidine*

Mariusz Jaskólski++, Wlodzimierz Krzyzosiak+, Hanna Sierzputowska-Gracz+ and Maciej Wiewiórowski+,{dagger}

+Institute of Bioorganic Chemistry, Polish Academy of Sciences ul. Noskowskiego 12/14, 61-704 Poznan ++Department of Crystallography, Institute of Chemistry, A.Mickiewicz University ul. Grunwaldzka 6, 60-780 Poznan, Poland

{dagger}Author to whom correspondence should be addressed

Received July 31, 1981.

The X-ray crystal and molecular structure of 3, N4 -ethenocytidine ({varepsilon}Cyd) has been solved and refined on counter data to R-0.038. A detailed discussion of the base electronic structure, molecular conformation and intermolecular interactions is the starting point for a comparative analysis of the series: Cyd, {varepsilon}Cyd, Cyd.HCl, and {varepsilon}Cyd.HCl. Protonation changes the base electronic structure and results in a completely different molecular conformation and intermolecular Interactions. Etheno—bridging does not alter the molecular conformation but it also changes the intermolecular interactions.

*Some parts of this paper were prsented at the following meetings:

  • Biological Implications of Protein-Nucleic Acid Interactions Poznan-Dymaczewo, May 1980

  • 3rd International Symposium of Crystal Organic Chemistry Poznan-Kiekrz, September 1980

  • 4th Round Table on Nucleosides, Nucleotides and their Biological Applications Antwerp, February 1981


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.