Skip Navigation

This Article
Right arrow Print PDF (977K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (9)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Rothberg, P. G.
Right arrow Articles by Wimmer, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rothberg, P. G.
Right arrow Articles by Wimmer, E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1981, Vol. 9, No. 23 6221-6230
© 1981

SURVEYS AND SUMMARIES

Mononucleotide and dinucleotide frequencies, and codon usage in poliovirion RNA

Paul G. Rothberg and Eckard Wimmer

Department of Microbiology, State University of New York at Stony Brook Stony Brook, NY 11794, USA

Received September 11, 1981. The polio type 1 (Mahoney) RNA sequence (1) has been analyzed in terms of the distribution of its mononucleotides, dinucleotides and trinucleotides (codons). The distribution of adenosine in the sequence is nonuniform, being Tower at the 5' end and higher at the 3' end. The dinucleotide CG is relatively rare and the dinucleotides UG and CA are relatively more common than expected. Codon usage is decidedly nonrandom. Codons containing CG are avoided and those ending in adenosine are favored. The asymmetric use of mononucleotides, dinucleotides and codons in polio RNA is unexplained at the present time although the lowered CG frequency may be the result of a DNA origin for polio RNA.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Virol.Home page
J. Jorba, R. Campagnoli, L. De, and O. Kew
Calibration of Multiple Poliovirus Molecular Clocks Covering an Extended Evolutionary Range
J. Virol., May 1, 2008; 82(9): 4429 - 4440.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
C. C. Burns, J. Shaw, R. Campagnoli, J. Jorba, A. Vincent, J. Quay, and O. Kew
Modulation of Poliovirus Replicative Fitness in HeLa Cells by Deoptimization of Synonymous Codon Usage in the Capsid Region.
J. Virol., April 1, 2006; 80(7): 3259 - 3272.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.